Carlo Giaquinto

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Anita De Rossi76
Diana M. Gibb46
Miriam C. J. M. Sturkenboom40
Timo Vesikari35
Luisa Galli31
70Anita De Rossi
48Miriam C. J. M. Sturkenboom
40Diana M. Gibb
35Marisa Zanchetta
31Susanna Esposito

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2017
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Distribution of rotavirus genotypes in Europe, 2004-2005: the REVEAL Study.
BACKGROUND Rotavirus gastroenteritis (RVGE) constitutes a significant burden of pediatric disease. Knowledge of currently cocirculating rotavirus genotypes is required to help guide immunization strategies. METHODS During the 2004-2005 RVGE season, a prospective, multicenter, observational study of RVGE was conducted in children <5 years of age seeking… (More)
Intussusception among young children in Europe.
Intussusception, a potentially lethal condition with poorly understood etiology, is the most common cause of acute intestinal obstruction in children younger than 5 years old. In some cases, the condition has been associated with administration of the first licensed rotavirus vaccine, the reassortant rhesus-human tetravalent rotavirus vaccine (RRV-TV;… (More)
Nosocomial rotavirus infection in European countries: a review of the epidemiology, severity and economic burden of hospital-acquired rotavirus disease.
The data currently available on the epidemiology, severity and economic burden of nosocomial rotavirus (RV) infections in children younger than 5 years of age in the major European countries are reviewed. In most studies, RV was found to be the major etiologic agent of pediatric nosocomial diarrhea (31-87%), although the number of diarrhea cases associated… (More)
Rotavirus types in Europe and their significance for vaccination.
The degree of diversity of cocirculating human rotavirus wild-type strains is high. This article reviews the occurrence and frequency of rotavirus types in European children younger than 5 years of age during the past 10-15 years. To enable greater understanding of the overall epidemiologic situation, rotavirus types found in animals in Europe are… (More)
Infants born to mothers seropositive for human immunodeficiency virus. Preliminary findings from a multicentre European study.
As part of a project within the European Community research activities on acquired immunodeficiency syndrome (AIDS), infants born to human-immunodeficiency-virus-seropositive mothers are being followed up from birth. By October, 1986, 71 infants from Padua, Berlin, and Edinburgh had been followed up to a median age of 6 months (range 1-15 months). Symptoms… (More)
Drug use in children: cohort study in three European countries
OBJECTIVE To provide an overview of drug use in children in three European countries. DESIGN Retrospective cohort study, 2000-5. SETTING Primary care research databases in the Netherlands (IPCI), United Kingdom (IMS-DA), and Italy (Pedianet). PARTICIPANTS 675 868 children aged up to 14 (Italy) or 18 (UK and Netherlands). MAIN OUTCOME MEASURE… (More)
Medicines for children licensed by the European Medicines Agency (EMEA): the balance after 10 years
The 1995–2005 balance of EMEA activities in the field of paediatric medicines was evaluated, taking into account the number both of drugs authorised for children and paediatric studies supporting the Marketing Authorisation (MA). Data on drugs authorised by EMEA were extracted from EPARs (European Public Assessment Reports). Active substance, year of… (More)
Clinical consequences of rotavirus acute gastroenteritis in Europe, 2004-2005: the REVEAL study.
BACKGROUND The availability of comprehensive, up-to-date epidemiologic data would improve the understanding of the disease burden and clinical consequences of rotavirus gastroenteritis (RVGE) in Europe. METHODS During the 2004-2005 season, a prospective, multicenter, observational study was conducted in children <5 years of age in primary care, emergency… (More)
Defining off-label and unlicensed use of medicines for children: results of a Delphi survey.
The aim of this Delphi survey is to develop common definitions for unlicensed and off-label drug use in children to be used for research and regulatory purposes. After a literature review on the current status of unlicensed/off-label definitions, a two-stage, web-based Delphi survey was conducted among experts in Europe. Their opinion on concerns, rules and… (More)
Multicenter prospective study of the burden of rotavirus acute gastroenteritis in Europe, 2004-2005: the REVEAL study.
BACKGROUND Rotavirus is recognized as a significant cause of pediatric gastroenteritis worldwide. Comprehensive data on the burden of rotavirus disease in Europe were lacking. METHODS A prospective, multicenter, observational study was conducted during the 2004-2005 season in selected areas of Belgium, France, Germany, Italy, Spain, Sweden, and the United… (More)