Carlo De Grandi

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BACKGROUND Posterior reversible leukoencephalopathy (PRES) is a clinical-radiological event that can affect children undergoing chemotherapy regimen. Studies have shown that it is not always reversible, in spite of its original definition. We analyzed PRES cases which occurred during the last 10 years at our institute to focus on their clinical,(More)
35 patients clinically diagnosed with transient ischemic attack (TIA) and 15 patients clinically diagnosed with reversible ischemic neurological deficits (RIND) were examined by computerized tomography (CT). 34% of TIA patients showed positive CT scans consisting of small hypodenase areas: 60% of RIND patients had larger lesions. In 20% of the overall group(More)
BACKGROUND AND PURPOSE Hemorrhagic transformation is frequently seen on CT scans obtained in the subacute phase of ischemic stroke. Its prognostic value is controversial. METHODS We analyzed 554 patients with acute ischemic stroke enrolled in the Multicenter Acute Stroke Trial-Italy (MAST-I) study in whom a second CT scan was performed on day 5. Presence(More)
BACKGROUND AND PURPOSE Diagnosis of hemorrhagic transformation (HT) could influence the prognosis and the management of acute ischemic stroke. The interobserver reliability of CT-scan HT classification is evaluated in the present study. METHODS Fifty 5-day CT scans of patients enrolled in the Multicenter Acute Stroke Trial-Italy (MAST-I) were reviewed(More)
TO THE EDITOR—Among human immu-nodeficiency virus (HIV)-infected patients on antiretroviral therapy (ART), incomplete viral suppression in cerebro-spinal fluid (CSF) may occur even with undetectable plasma viremia [1–4]. Treatment simplification with " less-drug regimens " may favor adherence and reduce toxicity, but raises concerns on lower central nervous(More)
Twelve patients with vascular malformations of the spinal cord have been treated by embolization at the Neuroradiological Department of the Ospedale Maggiore Niguarda Cà Granda from September 1981 to February 1984. Different materials and techniques have been used, including liophylised dura, Ivalon (PVA) and Isobutyl Cianoacrylate. All types of(More)
We engineer a quantum bath that enables entropy and energy exchange with a one-dimensional Bose-Hubbard lattice with attractive on-site interactions. We implement this in an array of three superconducting transmon qubits coupled to a single cavity mode; the transmons represent lattice sites and their excitation quanta embody bosonic particles. Our cooling(More)
Skull films of 5,570 patients older than 40 years of age admitted to the neurological (4,308), ophthalmologic (1,151), and otorhinolaryngologic clinics (111) of the University of Milan over a period of 20 years were reviewed for carotid siphon calcification. The 485 positive findings were divided into intimal and medial calcifications on the basis of(More)
45 children with ALL treated with intrathecal Methotrexate and radiation therapy, all in hematologic remission, have been examined with brain CT at intervals varying from 3 to 6 years after completion of CNS prophylaxis. Abnormalities were detected in 20% of the children; the main findings were: calcifications within the brain parenchyma in 3 patients;(More)