This study was designed to assess the effect of spinal cord injury on neurobehavioral, electrophysiological, structural, and biochemical changes in normal and diabetic rats. Experimental diabetes was induced in Sprague-Dawley male rats (weighing 250-280 g) with streptozotocin (50 mg/kg i.p.). Eight weeks after the treatment with streptozotocin the animals… (More)
Acrylamide (ACR) is a cumulative neurotoxin which causes axonal degeneration in animals and man. Industrial workers exposed to ACR have been reported to suffer from a variety of central and peripheral neuropathological symptoms including numbness of hands and feet, skin peeling and muscular weakness of legs. These reports suggest that the body burden of ACR… (More)
Purpose of the study Tailoring of antiretroviral therapy (ART) in HIV-2 remains unclear, therefore therapeutic experience in this population is presented. Methods Retrospective analysis of HIV-2 infected patients (pts) on ART followed at a single Portuguese center, between 1988 and 2010.
Central nervous system (CNS) diseases constitute a set of challenging pathological conditions concerning diagnosis and therapeutics. For most of these disorders, there is a lack of early diagnosis, biomarkers to allow proper follow-up of disease progression and effective therapeutic strategies to allow a persistent cure. The poor prognosis of most CNS… (More)
This paper proposes an ecological framework " Activities with Parents on the Computer " (APC) to bridge home and school contexts by involving parents and students in digital media based assignments. An exploratory case-study was conducted based on ten parent-child dyads that engaged in an APC at home. Attitudes were assessed through a self-evaluation… (More)
OBJECT This investigation was undertaken to study the effect of aluminum on neurobehavioral, electrophysiological, structural, and biochemical changes in rats following spinal cord injury (SCI). METHODS Adult male Sprague-Dawley rats classified into different groups were given aluminum sulfate-dosed drinking water in the concentrations of 0%, 0.25%, 0.5%… (More)