Carla Maria Sena Andrade Slater

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UNLABELLED The World Health Organization recommends the use of Osame's criterion (1990) for the diagnosis of HTLV-I-associated myelopathy (HAM/TSP). In 2006, a group of neurologists developed a Brazilian criterion that can diagnose HAM/TSP from its onset. OBJECTIVE It was to test the agreement between both criteria. METHODS The study included evaluation(More)
HTLV-I-associated myelopathy (HAM/TSP) is an inflammatory disease of the central nervous system (CNS) with an insidious onset and slowly progressive evolution1. The most common neurological manifestations include spastic paraparesis, sphincter dysfunction and sensory impairment. The diagnosis defined by HAM/TSP, according to the Osame criteria (1990), is(More)
Intrathecal synthesis of human T-lymphotropic virus type 1 (HTLV-1) antibodies (Abs) represents conclusive evidence of a specific immune response in the central nervous system of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. Western blotting (WB) for HTLV Abs in serum is a confirmatory test for HTLV-1 infection. The aim of(More)
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