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Telemonitoring is a tool with proven results demonstrating clinical benefits in reducing mortality and hospi-talizations. In this context, heart rate and rhythm are vital signs of utmost importance(More)
We investigated the mechanism by which T4 regulates its activation to T3 by the type 2 iodothyronine deiodinase (D2). D2 is a short- lived (t1/2 50 min), 31-kDa endoplasmic reticulum (ER) integral(More)
The type 2 monodeiodinase (D2) is an endoplasmic reticulum-resident membrane selenoprotein responsible for catalyzing the first step in thyroid hormone action, T(4) deiodination to T(3). Its short(More)