Carla J. H. van der Kallen

Suggest Changes
Learn More
BACKGROUND Low-grade inflammation has been hypothesized to underlie the coronary artery disease (CAD) risk associated with the metabolic syndrome, but the evidence is not conclusive. For peripheral(More)
OBJECTIVE Dysregulation of inflammatory adipokines by the adipose tissue plays an important role in obesity-associated insulin resistance. Pathways leading to this dysregulation remain largely(More)
BACKGROUND Diet may be associated with the development of type 2 diabetes through its effects on low-grade inflammation. OBJECTIVES We investigated whether an adapted dietary inflammatory index(More)
BACKGROUND Complement C3, a central component of the innate immune system is increased in subjects with obesity and type 2 diabetes and is a novel risk factor for cardiovascular disease. We(More)
CONTEXT Activating transcription factor 6 (ATF6) is critical for initiation and full activation of the unfolded protein response. An association between genetic variation in ATF6 and type 2 diabetes(More)