Carl Watson

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The continued globalization of pharmaceutics has increased the demand for companies to know and understand the regulations that exist across the globe. One hurdle facing pharmaceutical and biotechnology companies developing new drug candidates is interpreting the current regulatory guidance documents and industry publications associated with bioanalytical(More)
OBJECTIVE To objectively evaluate the usefulness and the reliability of the perineural vascular plexus as a landmark for identification of the facial nerve in surgery for chronic squamous otitis media. STUDY DESIGN Prospective case series. SETTING Tertiary otologic center. PATIENTS Seventy consecutive patients requiring surgery for cholesteatomatous(More)
OBJECTIVE To study the long-term recurrence rate of cholesteatoma with autoclaved incus autograft. STUDY DESIGN Prospective observational study between 1994 and 2009. The incus remnants were autoclaved at 134°C for 24 minutes at 205 kPa. The mean follow-up duration was 65.5 months, with a minimum follow-up duration of 31 months and a maximum follow-up(More)
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