Carl Watson

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In magnetic-stimulation studies where motor-evoked potentials (MEP) are measured on different occasions, accurate relocation of the stimulation site on the scalp is essential. Here a novel method of locating neural stimulation sites was tested and the reproducibility of MEPs in the human masseter assessed. The heads of the participants were immobilized in a(More)
The cortical topography of several limb and trunk muscles has been disclosed using transcranial magnetic stimulation, but the corticomotor representation of the human jaw muscles has not yet been described. An experimental paradigm incorporating transcranial magnetic stimulation of verified sites on the scalp was used (a) to determine the cortical(More)
Non-invasive magnetic stimulation of the brain was earlier used to reveal the corticomotor representation of the human masseter muscle but it is unclear how motor tasks affect this map. An experimental approach incorporating transcranial magnetic stimulation of verified locations on the scalp, surface electromyography, and controlled muscle facilitation was(More)
The continued globalization of pharmaceutics has increased the demand for companies to know and understand the regulations that exist across the globe. One hurdle facing pharmaceutical and biotechnology companies developing new drug candidates is interpreting the current regulatory guidance documents and industry publications associated with bioanalytical(More)
OBJECTIVE To study the long-term recurrence rate of cholesteatoma with autoclaved incus autograft. STUDY DESIGN Prospective observational study between 1994 and 2009. The incus remnants were autoclaved at 134°C for 24 minutes at 205 kPa. The mean follow-up duration was 65.5 months, with a minimum follow-up duration of 31 months and a maximum follow-up(More)
OBJECTIVE To objectively evaluate the usefulness and the reliability of the perineural vascular plexus as a landmark for identification of the facial nerve in surgery for chronic squamous otitis media. STUDY DESIGN Prospective case series. SETTING Tertiary otologic center. PATIENTS Seventy consecutive patients requiring surgery for cholesteatomatous(More)
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