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Combining positive attributes of planar arrays and suspension arrays, immobilized particle arrays offer a new format in which immobilized submicrometer particles are arrayed on hydrogel-coated slides, providing 100+ assay replicates within each spot. This research describes how to prepare immobilized protein arrays and how to assay the binding of labeled(More)
We construct and study the moduli of continuous representations of a profinite group with integral p-adic coefficients. We present this moduli space over the moduli space of continuous pseudorepresentations and show that this morphism is algebraizable. When this profinite group is the absolute Galois group of a p-adic local field, we show that these moduli(More)
Chemokines and their receptors are pivotal for the trafficking of leukocytes during immune responses, and host defense. However, immune cell migration also contributes to a wide variety of autoimmune and chronic inflammatory diseases. Compelling evidence suggests that both CXCR3 and CCR6 chemokine receptors play crucial roles in the migration of(More)
This is a brief summary of one part of the forthcoming work “Cohomological control of deformation theory via A∞-structure.” Let G be a profinite group. The main result is that a natural A∞-structure on cohomology groups induces presentations of universal deformation rings for G-representations, more general moduli spaces for G-representations, and universal(More)
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