Carl E Kramer

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Although studies have demonstrated that zinc can bind to sperm nuclear proteins, specifically protamine 2, it has not been shown that the metal is sufficiently abundant inside the sperm nucleus to interact stoichiometrically with these proteins. In this study proton-induced X-ray emission (PIXE) has been used to measure the amount of sulfur and zinc within(More)
We evaluated 104 radical prostatectomies for clinical stage B (n = 93) and stage A (n = 11) prostate cancer. Seven (8%) stage B cases had no gross cancer. By submitting only gross stage B cancer along with standard sections of proximal and distal margins, base of seminal vesicles, and most apical section (next to distal margin), we identified 91% of(More)
BACKGROUND Several noninvasive measurement approaches for the determination of blood glucose levels have been pursued over the past two decades. There is worldwide recognition that an unobtrusive and noninvasive measurement technique will better enable the patient with diabetes to obtain information for appropriate disease management. Many challenges have(More)
This study compares the frequency of prominent nucleoli in low-grade adenocarcinoma with that of its frequent mimicker, adenosis. One hundred thirteen transurethral resection specimens of stage A purely low-grade adenocarcinoma (only Gleason score 1 or 2) were evaluated. Eighteen cases of adenosis were evaluated for comparison. Prominent nucleoli were(More)
Basic nuclear proteins were isolated from the sperm of the Syrian hamster Mesocricetus auratus and characterized by gel electrophoresis, amino acid analysis, and sequencing. Analyses of the proteins by gel electrophoresis show that sperm of this species contain both protamines 1 and 2. The two proteins were purified by HPLC and the complete primary sequence(More)
PURPOSE To describe peripheral defocus when myopic eyes are corrected with spherical and center-distance multifocal soft contact lenses while looking at distance and near. METHODS Twenty-five young adults with spherical contact lens-corrected refractive error of -0.50 to -6.00 D participated. Refractive error of each participant's right eye was measured(More)
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