Carl Bosch

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To evaluate the sensitivity of the intravoxel incoherent motion (IVIM) technique to changes in cerebral blood flow, we made measurements of IVIM parameters in rat brain under conditions of altered arterial pCO2. The arterial pCO2 was varied over a range which would be expected to change cerebral blood flow from roughly 50 to 500 ml/(100 g.min). The IVIM(More)
A maximum-likelihood (ML)-based magnetic-resonance-imaging (MRI) reconstruction algorithm is established, based on frequency- and phase-encoded data. The model on which the ML method is based is a superposition of exponentially decaying, sinc-modulated sinusoids, arising from the basic Bloch equations for MR spectroscopy, modified to account for the(More)
—Three-dimensional x-ray CT image reconstruction in baggage scanning in security applications is an important research field. The variety of materials to be reconstructed is broader than medical x-ray imaging. Presence of high attenuating materials such as metal may cause artifacts if analytical reconstruction methods are used. Statistical modeling and the(More)
Diabetic nephropathy is a major cause of end-stage renal failure. While our understanding of the pathogenesis of nephropathy is incomplete, progressive glomerular injury appears to play a significant role in the decline of renal function. Proton NMR spectroscopy and imaging techniques were used to address changes in renal pathology associated with(More)
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