Carl B. Jackson

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The antiemetic activity of zacopride against a variety of emetogenic agents has been determined in dogs. Zacopride was highly effective in inhibiting emesis due to a wide range of cancer chemotherapeutic agents, particularly cisplatin. It was well absorbed orally since the dose of zacopride required to inhibit cisplatin-induced emesis in dogs by 90% was 28(More)
Why business impact assessment? The reason that the business impact assessment (BIA) element of the business continuity planning (BCP) methodology takes on such significance is that it sets the stage for shaping a business-oriented judgment concerning the appropriation of resources for recovery planning efforts. Our experiences in this area have shown that,(More)
has seized the spotlight and Web-based technologies are the emerging solution for almost everything. The constant throughout these occurrences is that no matter what the climate, fundamental business processes have changed little. And, as always, the focus of any business impact assessment is to assess the time-critical priority of these business processes.(More)
Zacopride administered orally was more emetic in fed than in fasted ferrets. The emetic activity of zacopride (0.1 mg/kg p.o.) was inhibited (100%) by 0.1 mg/kg i.p. of zacopride and 1 mg/kg i.p. of ICS 205-930. Haloperidol (3.16 mg/kg i.p.) and prochlorperazine (3.16 mg/kg i.p.) were weakly effective. N-acetyl-5-hydroxytryptophyl-5-hydroxytryptophan amide,(More)