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We developed a test that compares sequential measurements of a biomarker against previous readings performed on the same individual. A probability mass function expresses prior information on interindividual variations of intraindividual parameters. Then, the model progressively integrates new readings to more accurately quantify the characteristics of the(More)
BACKGROUND AND OBJECTIVES Urinary steroid profiling is used in doping controls to detect testosterone abuse. A testosterone over epitestosterone (T/E) ratio exceeding 4.0 is considered as suspicious of testosterone administration, irrespectively of individual heterogeneous factors such as the athlete's ethnicity. A deletion polymorphism in the UGT2B17 gene(More)
The screening of testosterone (T) misuse for doping control is based on the urinary steroid profile, including T, its precursors and metabolites. Modifications of individual levels and ratio between those metabolites are indicators of T misuse. In the context of screening analysis, the most discriminant criterion known to date is based on the T glucuronide(More)
BACKGROUND The FIFA has implemented an important antidoping programme for the 2014 FIFA World Cup. AIM To perform the analyses before and during the World Cup with biological monitoring of blood and urine samples. METHODS All qualified players from the 32 teams participating in the World Cup were tested out-of-competition. During the World Cup, 2-8(More)
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