Caren Wilsch

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PURPOSE In vitreoretinopathy membranes and in vitro, RPE cells lose pigment and transform into fibroblast-like cells. The purpose of this study was to investigate whether the immune privileged status of different eye compartments influence morphological changes of adult RPE cell transplants. METHODS RPE cells from adult C57BL/6 mice were transplanted(More)
The sequence of degenerative changes in the retinal pigment epithelium (RPE) and the choroid of retinal degeneration (rd)-mice was studied in correlation with photoreceptor changes. Three weeks to 26-month-old animals were investigated using light and transmission electron microscopy, enzyme histochemistry and quantitative morphology. Changes in the(More)
PURPOSE To determine whether the capacity to induce ACAID by antigen injection into the anterior chamber is altered in animals with genetically determined retinal degeneration and increased age. METHODS Anterior chamber-associated immune deviation (ACAID) induced by injection of ovalbumin into the anterior chamber of the eye was studied in three rodent(More)
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