Can Chen

Publications68
h-index14
Citations542
Highly Influential Citations21
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Functional characterization of a mycothiol peroxidase in Corynebacterium glutamicum that uses both mycoredoxin and thioredoxin reducing systems in the response to oxidative stress.
TLDR
The MPx function is investigated by examining its potential peroxidase activity using different proton donors and it is proposed that the C. glutamicum MPx represents a new type of GPx that uses both mycoredoxin and Trx systems for oxidative stress response. Expand
Functional characterization of a vanillin dehydrogenase in Corynebacterium glutamicum
TLDR
The vdh deletion mutant partially lost its ability to grow on vanillin, indicating the presence of alternative VDH(s) in Corynebacterium glutamicum and contributes to understanding the VDH diversity from bacteria and the aromatic metabolism pathways in C. glutamum. Expand
Confirmed and Potential Roles of Bacterial T6SSs in the Intestinal Ecosystem
TLDR
Considering the distinct activities of T6SS in diverse bacteria residing in the intestine, it is suggested that T 6SS research in intestinal microbes may be beneficial for the future development of new medicines and clinical treatments. Expand
Trichoderma harzianum containing 1-aminocyclopropane-1-carboxylate deaminase and chitinase improved growth and diminished adverse effect caused by Fusarium oxysporum in soybean.
TLDR
Reactive oxygen species (ROS) scavenging enzymes activity analysis showed that the activities of peroxidase (POD), polyphenol oxidase (PPO) and superoxide dismutase (SOD) increased significantly in T- soybean pretreated plants, suggesting that T-soybean treatment induced resistance in soybean seedlings to F. oxysporum. Expand
Catalytic decomposition of toxic chemicals over iron group metals supported on carbon nanotubes.
TLDR
Cobalt phosphide formed on Co/C NTs and Co(3)O4/CNTs exhibits not only the highest activity, but also long-term stability in the PH3 decomposition reaction. Expand
Corynebacterium glutamicum Methionine Sulfoxide Reductase A Uses both Mycoredoxin and Thioredoxin for Regeneration and Oxidative Stress Resistance
TLDR
It is reported that a Corynebacterium glutamicum methionine sulfoxide reductase A (CgMsrA) that belongs to the 3-Cys family of MsrAs plays important roles in oxidative stress resistance. Expand
Mycothiol protects Corynebacterium glutamicum against acid stress via maintaining intracellular pH homeostasis, scavenging ROS, and S-mycothiolating MetE.
TLDR
Evidence is presented that MSH confers C. glutamicum with the ability to adapt to acidic conditions by maintaining pHi homeostasis, scavenging reactive oxygen species (ROS), and protecting methionine synthesis by the S-mycothiolation modification of Methionine synthase (MetE). Expand
OhsR acts as an organic peroxide-sensing transcriptional activator using an S-mycothiolation mechanism in Corynebacterium glutamicum
TLDR
This is the first report demonstrating that the regulatory OhsR specifically sensed OHPs stress and responded to it by activating a specific ohr gene under its control using an S-mycothiolated mechanism in vivo. Expand
Graded Response of the Multifunctional 2-Cysteine Peroxiredoxin, CgPrx, to Increasing Levels of Hydrogen Peroxide in Corynebacterium glutamicum.
TLDR
It is demonstrated for the first time that atypical 2-Cys CgPrx acts as both a Trx-dependent peroxidase and a molecular chaperone and plays a regulatory role in modulating the peroxide-mediated signaling cascades. Expand
Molecular mapping of stripe rust resistance gene YrJ22 in Chinese wheat cultivar Jimai 22
TLDR
Genetic analysis of F2 and F2:3 populations from an Avocet S/Jimai 22 cross indicated that stripe rust resistance in Jimai 22 was conferred by a single dominant gene, tentatively designated YrJ22, which is likely to be a new wheat stripes rust resistance gene. Expand
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