Camila Giro

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Common functional polymorphisms in β-adrenergic receptor (βAR) genes have been associated with heart failure (HF) phenotypes and pharmacogenetic interactions with βAR blockers. This study evaluated the association between βAR polymorphisms and carvedilol drug response and prognosis in patients with HF. In this prospective cohort controlled study, 326(More)
BACKGROUND The reduction in mortality from cardiovascular disease has been observed in Brazil for years, attributed to a fall in risk factors, improved treatment and reduced hospital mortality. OBJECTIVE To compare the mortality, the rate of hospitalization and hospital mortality in hospitals belonging to the Brazilian Public Health System, for ischemic(More)
Heart failure (HF) is a complex disease, which involves several physiopathological mechanisms and different genetic polymorphisms. The adrenergic system is directly related to this pathology, as it participates in cardiovascular autoregulation and has a crucial role in the deterioration of cardiac function. The beta-blockers appeared as a great advance in(More)
BACKGROUND Previous studies have analyzed the role of the genetic polymorphism of endothelial nitric oxide synthase on heart failure prognosis. However, there are no studies relating the G894T and heart failure in Brazil. OBJECTIVE To evaluate the association between G894T GP and the prognosis of a sample of Brazilian outpatients with heart failure. (More)
Mailing address: Thiago de Oliveira e Alves • Rua Marquês de Paraná, 303, 6 andar, Cardiologia Centro 24220-111 Niterói, RJ Brazil E-mail: oliveiraealves@gmail.com, thibiomed@hotmail.com Manuscript received August 30, 2010; revised manuscript received November 11, 2010, accepted on December 07, 2010. Abstract Background: The reduction in mortality from(More)