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Early Prediction of Intensive Care Unit–Acquired Weakness Using Easily Available Parameters: A Prospective Observational Study
Introduction An early diagnosis of Intensive Care Unit–acquired weakness (ICU–AW) using muscle strength assessment is not possible in most critically ill patients. We hypothesized that development ofExpand
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Muscle and nerve inflammation in intensive care unit-acquired weakness: A systematic translational review
BACKGROUND Intensive care unit-acquired weakness (ICU-AW) is an important complication of critical illness. The main risk factors, sepsis and the systemic inflammatory response syndrome, suggest anExpand
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Increased Early Systemic Inflammation in ICU-Acquired Weakness; A Prospective Observational Cohort Study*
Objectives: To investigate whether patients who develop ICU-acquired weakness have a different pattern of systemic inflammatory markers compared with critically ill patients who do not developExpand
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Feasibility and Diagnostic Accuracy of Early Electrophysiological Recordings for ICU-Acquired Weakness: An Observational Cohort Study
BackgroundAn early diagnosis of ICU-acquired weakness (ICU-AW) is difficult because disorders of consciousness frequently preclude muscle strength assessment. In this study, we investigatedExpand
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Nerve ultrasound
Objective To determine interobserver variability of nerve ultrasound in peripheral neuropathy in a prospective, systematic, multicenter study. Methods We enrolled 20 patients with an acquired chronicExpand
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Assessment of intensive care unit‐acquired weakness in young and old mice: An E. coli septic peritonitis model
Introduction: There are few reports of in vivo muscle strength measurements in animal models of ICU‐acquired weakness (ICU‐AW). In this study we investigated whether the Escherichia coli (E. coli)Expand
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Diagnostic accuracy of MRI and ultrasound in chronic immune-mediated neuropathies
Objective To assess and compare the diagnostic performance of qualitative and (semi-)quantitative MRI and ultrasound for distinguishing chronic inflammatory demyelinating polyneuropathy (CIDP) andExpand
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Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy
Background: Clinical and experimental data show that peripheral nerve blocks last longer in the presence of diabetic neuropathy. This may occur because diabetic nerve fibers are more sensitive toExpand
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Increased early systemic inflammation in patients with ICU-acquired weakness
Inflammation may be important in the pathogenesis of ICU-acquired weakness (ICU-AW) since SIRS, sepsis and multiple organ failure are the main risk factors. Local inflammation has been found inExpand
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