Cameron Wellock

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Researchers in quantitative systems biology make use of a large number of different software packages for modelling, analysis, visualization, and general data manipulation. In this paper, we describe the Systems Biology Workbench (SBW), a software framework that allows heterogeneous application components--written in diverse programming languages and(More)
The singing of juvenile songbirds is highly variable and not well stereotyped, a feature that makes it difficult to analyze with existing computational techniques. We present here a method suitable for analyzing such vocalizations, windowed spectral pattern recognition (WSPR). Rather than performing pairwise sample comparisons, WSPR measures the typicality(More)
The usual form of the Problem-Oriented Medical Record is primarily focused on the individual, and thus has serious deficiencies for the family-oriented physician. This paper presents a practical, office-tested medical charting system that incorporates features of the Problem-Oriented Medical Record and allows the recording of aspects of the family situation(More)
As a contribution to the BioSPICE project, we have developed an optimization module, for the task of fitting kinetic rate constants to time series concentration data. The algorithms use, both local searches, such as the Levenberg-Marquardt, and simplex, as well as global search methods such as simulated annealing and real coded genetic algorithms. We(More)
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