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Mitogen-activated protein (MAP) kinases are proline-directed, serine/threonine kinases that respond to a variety of extracellular signals. A subgroup of these kinases, stress-activated protein (SAP) kinases, phosphorylate c-jun in response to cellular stress. Using monoclonal antibody (MAb) 3F12, we have cloned and partially characterized p493F12 kinase, a(More)
The T2K experiment has observed electron neutrino appearance in a muon neutrino beam produced 295 km from the Super-Kamiokande detector with a peak energy of 0.6 GeV. A total of 28 electron neutrino events were detected with an energy distribution consistent with an appearance signal, corresponding to a significance of 7.3σ when compared to 4.92±0.55(More)
Spin-dependent lepton-nucleon scattering data have been used to investigate the validity of the concept of quark-hadron duality for the spin asymmetry A1. Longitudinally polarized positrons were scattered off a longitudinally polarized hydrogen target for values of Q2 between 1.2 and 12 GeV2 and values of W2 between 1 and 4 GeV2. The average double-spin(More)
The T2K experiment observes indications of ν(μ) → ν(e) appearance in data accumulated with 1.43×10(20) protons on target. Six events pass all selection criteria at the far detector. In a three-flavor neutrino oscillation scenario with |Δm(23)(2)| = 2.4×10(-3)  eV(2), sin(2)2θ(23) = 1 and sin(2)2θ(13) = 0, the expected number of such events is 1.5±0.3(syst).(More)
The HERMES experiment is collecting data on inclusive and semi-inclusive deep inelastic scattering of polarised positrons from polarised targets of H, D, and 3 He. These data give information on the spin structure of the nucleon. This paper describes the forward angle spectrometer built for this purpose. The spectrometer includes numerous tracking chambers(More)
1 Abstract Polarized leptoproduction of charm is an experimentally completely unexplored and theoretically very interesting topic. Of particular interest in this area is the potential sensitivity of the polarization asymmetry to the contribution of the gluons to the nucleon spin. The present HERMES spectrometer is far from optimal for detecting the most(More)
The proton is a composite object with spin one-half, understood to contain highly relativistic spin one-half quarks exchanging spin-one gluons, each possibly with significant orbital angular momenta. While their fundamental interactions are well described by Quantum ChromoDynamics (QCD), our standard theory of the strong interaction, nonperturbative(More)
The SPIN Collaboration and the DESY Polarization Team have studied the possible acceleration of a polarized proton beam to 820 GeV/c in the HERA accelerator complex at DESY. The main problems which need further study are: increasing the accumulated polarized proton intensity, providing adequate spin stability with four or more Siberian snakes in HERA. All(More)