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We studied the relationship between creatinine concentration in plasma and body size in 673 healthy individuals (385 women, 288 men). Weight, height, and skinfold thickness were measured and blood was sampled (after a short fast) for estimations of urea and creatinine in plasma. Lean body mass was calculated according to Durnin and Wormsley (Br J Nutr 1974;(More)
We studied the changes in blood glucose concentration in blood samples collected in heparinized specimen tubes containing no other preservative, or containing NaF, D-mannose, or a combination of NaF and D-mannose. Blood concentration in samples taken into NaF decreased by 0.40 mmol/L in the first 2 h; thereafter, there was no change. In samples collected(More)
Alpha-fetoprotein (AFP) is widely used as a serological marker in the diagnosis of hepatocellular carcinoma (HCC) and non-seminomatous germ cell tumours (NSGCT). By application of isoelectric focusing (IEF) disease-specific AFP isoforms can be identified. Three major bands are apparent: + 1 (associated with 'benign' liver disease), + II (associated with(More)
Although estimation of serum alpha-fetoprotein (AFP) is widely used in the diagnosis of hepatocellular carcinoma (HCC) and non-seminomatous germ cell tumours (NSGCT), the clinical usefulness of this test is limited by a low specificity. However, there exist glycoforms of AFP which may be more specific for particular tumours. Previously, detailed analysis(More)
brovascular occlusive disease, or from peripheral arterial occlusive disease. As shown in Table 1, there were distinctly higher homocysteine concentrations for seropositive subjects in subgroups of age, renal function, smoking status, and MTHFR gene mutations. These variables influencing serum homocysteine, as well as vitamin B 6 , vitamin B 12 , and folic(More)
research interests include vascular dementia, Parkinson's disease and stroke. He has published more than 100 peer-reviewed articles and is the author of several book chapters in vascular dementia and Parkinson's disease. Executive dysfunction and left frontal white matter hyperintensities are correlated with neuropsychiatric symptoms in stroke patients with(More)
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