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The frequency and poor prognosis of patients with metastatic colorectal cancer (mCRC) emphasizes the requirement for improved biomarkers for use in the treatment and prognosis of mCRC. In the present study, somatic variants in exonic regions of key cancer genes were identified in mCRC patients. Formalin‑fixed, paraffin‑embedded tissues obtained by biopsy of(More)
OBJECTIVE To obtain the anti-HAV antibodies. METHODS The antibody-capturing antigen strategy was used in panning antibody library with impure antigen. The HAV-binding activity and specificity of phage antibodies were assayed by sandwich ELISA and competitive inhibition ELISA. RESULTS Phage antibodies(Fab) against HAV were screened from a human(More)
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