CG Owens

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Adenosine deaminase deficiency is a disorder of purine metabolism manifesting severe combined immunodeficiency (ADA-SCID) and systemic abnormalities. Increased levels of the substrate deoxyadenosine triphosphate (dATP) lead to immunodeficiency and are associated in a murine model with pulmonary insufficiency. We compared a cohort of patients with ADA-SCID(More)
People with Cystic Fibrosis have a high risk of MRSA infection. Prevalence has increased from 7% of patients in 2001 to 17.2% of patients in 2005 in the USA (1). It is unclear whether MRSA respiratory infection influences lung function, which antibiotics (if any) should be used to treat MRSA infection and for how long. This study investigates the prevalence(More)
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