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To develop a malleable system to model the well-described, physiological interactions between Gq/11 - coupled receptor and Gi/o-coupled receptor signaling, we coexpressed the endothelin A receptor, the mu-opioid receptor, and the G protein-coupled inwardly rectifying potassium channel (Kir 3) heteromultimers in Xenopus laevis oocytes. Activation of the(More)
The members of the Committee appointed to examine the dissertation of MICHELLE CATHERINE CYR WIDOLFF find it satisfactory and recommend that it be accepted. ACKNOWLEDGEMENTS I would like to thank Michael Morgan for his continued guidance and support during my time as a graduate student at Washington State University. His help has been invaluable and without(More)
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