CA Clement

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TGFb signaling extensively cross-talks with Hh, Wnt and RTK signaling to control cell proliferation, migration and differentiation, and when aberrantly regulated leads to developmental defects and cancer. TGFb signaling is activated through the internalization of TGFb receptors via clathrin-dependent endocytosis (CDE), at which the receptor activates Smad(More)
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