CA Clement

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An isolate of Salmonella enteritidis was found to produce a plasmid-encoded beta-lactamase (DHA-1) that conferred resistance to extended-spectrum cephalosporins and cephamycins. The substrate and inhibition profiles of this enzyme resemble a class C beta-lactamase. This is the first report of a plasmid-mediated cephalosporinase of this class in the(More)
TGFb signaling extensively cross-talks with Hh, Wnt and RTK signaling to control cell proliferation, migration and differentiation, and when aberrantly regulated leads to developmental defects and cancer. TGFb signaling is activated through the internalization of TGFb receptors via clathrin-dependent endocytosis (CDE), at which the receptor activates Smad(More)
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