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Urothelial lesions in Chinese-herb nephropathy.
Rapidly progressive renal fibrosis after a slimming regimen including Chinese herbs containing aristolochic acid (AA) has been identified as Chinese-herb nephropathy (CHN). We reported urothelialExpand
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Advanced glycation and lipoxidation end products: role of reactive carbonyl compounds generated during carbohydrate and lipid metabolism.
The uremic syndrome is usually attributed to the retention of a variety of compounds as a result of a deficient renal clearance. These retention solutes are taken to induce biochemical disordersExpand
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Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy.
A unique type of rapidly progressive renal fibrosis, designated Chinese herbs nephropathy (CHN), has been described in young Belgian women who had followed a slimming regimen including recentlyExpand
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Glucose degradation product methylglyoxal enhances the production of vascular endothelial growth factor in peritoneal cells: role in the functional and morphological alterations of peritoneal
Peritoneal membrane permeability deteriorates in peritoneal dialysis (PD) patients. We test whether glucose degradation products (GDPs) in PD fluids, glyoxal, methylglyoxal and 3‐deoxyglucosone,Expand
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Implication of an increased oxidative stress in the formation of advanced glycation end products in patients with end-stage renal failure.
Recent studies have demonstrated a marked increase in the level of advanced glycation end products (AGEs) in the plasma, skin and amyloid fibrils of hemodialysis (HD) patients. The presence of AGEsExpand
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Chinese herbs nephropathy: a clue to Balkan endemic nephropathy?
Rapidly progressive interstitial renal fibrosis has recently been reported in young women who have been on a slimming regimen including Chinese herbs. We examined four nephroureterectomies performedExpand
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Chinese herbs nephropathy presentation, natural history and fate after transplantation.
BACKGROUND Chinese herbs nephropathy is a new type of subacute interstitial nephropathy reported in women who had followed a slimming regimen including Chinese herbs. METHODS We report the clinicalExpand
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Alterations in nonenzymatic biochemistry in uremia: origin and significance of "carbonyl stress" in long-term uremic complications.
Advanced glycation end products (AGEs), formed during Maillard or browning reactions by nonenzymatic glycation and oxidation (glycoxidation) of proteins, have been implicated in the pathogenesis ofExpand
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Renal catabolism of advanced glycation end products: the fate of pentosidine.
Advanced glycation end products (AGEs) generated through the Maillard reaction significantly alter protein characteristics. Their accumulation has been incriminated in tissue injury associated withExpand
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Glyoxalase I deficiency is associated with an unusual level of advanced glycation end products in a hemodialysis patient.
BACKGROUND Advanced glycation of proteins and their attendant advanced glycation end products (AGEs) contribute to the complications associated with diabetes mellitus or uremia. Regulatory mechanismsExpand
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