C. van Schalkwyk

Publications32
h-index15
Citations766
Highly Influential Citations45
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Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa
TLDR
Analysis of routine surveillance data from South Africa suggests that, in contrast to the Beta and Delta, the Omicron variant of SARS-CoV-2 demonstrates substantial population-level evidence for evasion of immunity from prior infection.
Tuberculosis in Healthcare Workers and Infection Control Measures at Primary Healthcare Facilities in South Africa
TLDR
The high rate of TB in healthcare workers suggests a substantial nosocomial transmission risk, but the infection control audit tool which was used did not perform adequately as a measure of this risk.
Projected early spread of COVID-19 in Africa through 1 June 2020
For 45 African countries/territories already reporting COVID-19 cases before 23 March 2020, we estimate the dates of reporting 1,000 and 10,000 cases. Assuming early epidemic trends without…
Estimating the magnitude of pulmonary tuberculosis patients missed by primary health care clinics in South Africa.
TLDR
Universal TB screening and testing of symptomatic individuals should be instituted in high TB burden communities in South Africa because low rates of TB screenings and testing by the health system resulted in missed TB patients.
High Prevalence of Tuberculosis and Insufficient Case Detection in Two Communities in the Western Cape, South Africa
TLDR
In both communities a higher TB prevalence than national estimates and a low patient diagnostic rate was calculated, suggesting that cases are not detected at a sufficient rate to interrupt transmission.
Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa
TLDR
Analysis of routine surveillance data from South Africa indicates that the Omicron variant of SARS-CoV-2 evades immunity from prior infection, and this variant does not fully evade vaccine-derived immunity, but only those privileged to have been vaccinated can benefit.
Understanding and acting on the developmental origins of health and disease in Africa would improve health across generations
TLDR
It is argued that the application of DOHaD science in Africa to advance life-course prevention programmes can aid the achievement of the Sustainable Development Goals, and assist in improving health across generations.
High human papillomavirus (HPV) prevalence in South African adolescents and young women encourages expanded HPV vaccination campaigns
TLDR
The high burden of BV and concurrent STIs also highlights the need to improve the prevention and appropriate management of sexually-acquired and other genital tract infections in South African youth.
Incidence of TB and HIV in Prospectively Followed Household Contacts of TB Index Patients in South Africa
TLDR
In the year following a household case finding visit when household contacts were tested forTB and HIV, the incidence rate of both active TB and HIV infection was found to be extremely high.
Birth outcomes following antiretroviral exposure during pregnancy: Initial results from a pregnancy exposure registry in South Africa
TLDR
No association between T1 use of EFV-based ART regimens and CM was observed and Associations between T2 NVP- based ART regimen and CM need further investigation.
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