C. la Vecchia

Publications2,006
h-index150
Citations105,730
Highly Influential Citations3,366
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Epidemiology and risk factors of urothelial bladder cancer.
TLDR
UBC is a frequently occurring malignancy with a significant impact on public health and will remain so because of the high prevalence of smoking and the importance of primary prevention must be stressed and smoking cessation programs need to be encouraged and supported. Expand
Risk Factors for Falls in Community-dwelling Older People: A Systematic Review and Meta-analysis
TLDR
This meta-analysis provides comprehensive evidence-based assessment of risk factors for falls in older people, confirming their multifactorial etiology and finding some nonspecific indicators of high baseline risk were also strong predictors of the risk of falling. Expand
A meta-analysis of alcohol consumption and the risk of 15 diseases.
TLDR
This meta-analysis shows no evidence of a threshold effect for both neoplasms and several non-neoplastic diseases, and J-shaped relations were observed only for coronary heart disease. Expand
Gallbladder cancer worldwide: Geographical distribution and risk factors
TLDR
Differences in incidence ratios point to variations in gallbladder cancer aetiology in different populations, but interventions able to prevent obesity, cholecystitis and gallstone formation should be assessed. Expand
Interaction between Tobacco and Alcohol Use and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium
TLDR
It is confirmed that the joint effect between tobacco and alcohol use is greater than multiplicative on head and neck cancer risk, however, a substantial proportion of head and head cancers cannot be attributed to tobacco or alcohol use, particularly for oral cavity cancer and for head andneck cancer among women and among young-onset cases. Expand
Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial
TLDR
There was no evidence of a protective effect of annual or biennial LDCT screening, and a meta-analysis of the four published randomized trials showed similar overall mortality in the LDCT arms compared with the control arm. Expand
Recent patterns in gastric cancer: A global overview
TLDR
Steady downward trends persist in gastric cancer mortality worldwide even in middle aged population, and hence further appreciable declines are likely in the near future. Expand
Epidemiology and aetiology of gestational trophoblastic diseases.
TLDR
Broad variations in the distribution of GTD exist worldwide, with higher frequencies in some parts of Asia, the Middle East and Africa, but the extent to which they can be attributed to methodological difficulties in obtaining accurate rates is unclear. Expand
Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis
TLDR
Alcohol increases risk of cancer of oral cavity and pharynx, oesophagus, colorectum, liver, larynx and female breast, and there is accumulating evidence that alcohol drinking is associated with some other cancers such as pancreas and prostate cancer and melanoma. Expand
The burden of cancer attributable to alcohol drinking
TLDR
Although the authors' estimates are based on simplified assumptions, the burden of alcohol‐associated cancer appears to be substantial and needs to be considered when making public health recommendations on alcohol drinking. Expand
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