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Compensatory enlargement of human atherosclerotic coronary arteries.
It is concluded that human coronary arteries enlarge in relation to plaque area and that functionally important lumen stenosis may be delayed until the lesion occupies 40 percent of the internal elastic lamina area. Expand
Pulsatile Flow and Atherosclerosis in the Human Carotid Bifurcation: Positive Correlation between Plaque Location and Low and Oscillating Shear Stress
These studies confirm earlier findings under steady flow conditions that plaques tend to form in areas of low, rather than high, shear stress, but indicate in addition that marked oscillations in the direction of wall shear may enhance atherogenesis. Expand
Reporting standards for endovascular aortic aneurysm repair.
This work is presented for the first time to the Ad Hoc Committee for Standardized Reporting Practices in Vascular Surgery of The Society for Vascular surgery/American Association forVascular Surgery. Expand
Carotid Bifurcation Atherosclerosis: Quantitative Correlation of Plaque Localization with Flow Velocity Profiles and Wall Shear Stress
It is concluded that in the human carotid bifurcation, regions of moderate to high shear stress, where flow remains unidirectional and axially aligned, are relatively spared of intimal thickening. Expand
Nature and significance of endoleaks and endotension: summary of opinions expressed at an international conference.
The current endoleak classification system with some important modifications is adequate and should help to resolve controversy and aid in the management of these vexing complications and should also point the way to future research in this field. Expand
Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries.
Development of clinical techniques for relating hemodynamic and tensile properties to plaque location, stenosis, and composition should permit pathologists to provide new insights into the bases for the topographic and individual differences in plaque progression and outcome. Expand
Identifying and grading factors that modify the outcome of endovascular aortic aneurysm repair.
Comorbidity and anatomic schemes are offered as an initial effort to develop useful tools for the comparative analysis of data related to endovascular treatment of aortic aneurysm repair. Expand
Anastomotic intimal hyperplasia: mechanical injury or flow induced.
This investigation investigated the localization of experimental anastomotic intimal thickening in relation to known biomechanical and hemodynamic factors and revealed two separate and distinct regions of anastsomotic Intimal Thickening. Expand
Finite element modeling of blood flow in arteries
Abstract A comprehensive finite element framework to enable the conduct of computational vascular research is described. The software system developed provides an integrated set of tools to solveExpand
The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imaging.
This high resolution three-dimensional view of the aortic media reveals MLU microstructure details that suggest a highly complex and integrated mural organization that correlates with aortsic mechanical properties. Expand