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Suppressed NF-kappaB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-alpha-induced apoptosis in human cancer cells.
Parthenolide (PN) is the main sesquiterpene lactone found in feverfew with potent anti-inflammatory function. The anticancer property of PN has been demonstrated in both in vitro cell culture and inExpand
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DNA damage, apoptosis and C-myc, C-fos, and C-jun overexpression induced by selenium in rat hepatocytes.
OBJECTIVE To study the effects of selenium on DNA damage, apoptosis and c-myc, c-fos, and c-jun expression in rat hepatocytes. METHODS Sodium selenite at the doses of 5, 10, and 20 micromol/kg wasExpand
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Anti-diabetic effect of oligosaccharides from seaweed Sargassum confusum via JNK-IRS1/PI3K signalling pathways and regulation of gut microbiota.
Brown seaweed Sargassum confusum (C. Agardh) has been used in traditional Chinese medicine to treat a variety of diseases. The aim of the present study was to evaluate the anti-diabetic effect ofExpand
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Suppressed NFk B and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-a-induced apoptosis in human cancer cells
Siyuan Zhang, Zhong-Ning Lin, Cheng-Feng Yang, Xianglin Shi, Choon-Nam Ong and Han-Ming Shen Department of Community, Occupational and Family Medicine, Faculty of Medicine (MD3), National UniversityExpand
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Experimental investigation on film cooling characteristics from a row of holes with ridge-shaped tabs
Abstract Experimental study was conducted to investigate the enhanced cooling performance caused by ridge-shaped tabs located along the upstream edge of the film cooling holes. Three covering ratiosExpand
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Adenovirus‐mediated gene transfer of wild‐type p53 results in melanoma cell apoptosis in vitro and in vivo
Gene transfer techniques may provide efficient treatment for a variety of malignant neoplasms. A replication‐deficient adeno‐virus (Ad) vector which carries the cDNA for wild‐type p53 (AdCMV.p53) wasExpand
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Encapsulated Diverse Water Aggregates in Two Ag(I)/4,4 '-Bipyridine/Dicarboxylate Hosts: 1D Water Tape and Chain
National Natural Science Foundation of China [20721001]; MSTC [2007CB815301]; The National Science Fund of China for Fostering Talents in Basic Science [J0630429]
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Synthesis, characterization and property of a mixed-valent Ag(I)/Ag(II) coordination polymer.
A novel mixed-valent Ag(I)/Ag(II) coordination polymer {[Ag(I)(2)Ag(II)(0.5)(SO(4))(HSO(4))(pyz)(2.5)]·H(2)O}(n) (1, pyz = pyrazine) was synthesized and characterized. The results show it presentsExpand
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pH-Dependent Ag(I) coordination architectures constructed from 4-cyanopyridine and phthalic acid: from discrete structure to 2D sheet
Four mixed-ligand Ag(I) coordination complexes (CCs), namely, [Ag(cnpy)2(Hpta)] (1), [Ag2(cnpy)2(Hpta)2] (2), [Ag4(cnpy)2(pta)2(H2O)]n (3) and [Ag2(inta)2(pta)·3H2O]n (4), (cnpy = 4–cyanopyridine,Expand
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A lamella 2D silver(I) coordination polymer constructed from in situ generated 2-mercaptobenzoic acid
National Natural Science Foundation of China [20721001]; MSTC [2007CB815301]; National Science Fund of China for Fostering Talents in Basic Science [J0630429]
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