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eIF5A Functions Globally in Translation Elongation and Termination.
- Anthony P. Schuller, C. Wu, T. E. Dever, Allen R Buskirk, R. Green
- Medicine, Biology
- Molecular cell
- 20 April 2017
The eukaryotic translation factor eIF5A, originally identified as an initiation factor, was later shown to promote translation elongation of iterated proline sequences. Using a combination of… Expand
High-Resolution Ribosome Profiling Defines Discrete Ribosome Elongation States and Translational Regulation during Cellular Stress.
Ribosomes undergo substantial conformational changes during translation elongation to accommodate incoming aminoacyl-tRNAs and translocate along the mRNA template. We used multiple elongation… Expand
T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy.
Clinical observations and laboratory evidence link bone marrow failure in myelodysplastic syndrome (MDS) to a T cell-mediated immune process that is responsive to immunosuppressive treatment (IST) in… Expand
LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice.
- A. Armstrong, S. Gidding, O. Gjesdal, C. Wu, D. Bluemke, J. Lima
- JACC. Cardiovascular imaging
- 1 August 2012
The authors investigated 3 important areas related to the clinical use of left ventricular mass (LVM): accuracy of assessments by echocardiography and cardiac magnetic resonance (CMR), the ability to… Expand
Intakes of long-chain n-3 polyunsaturated fatty acids and fish in relation to measurements of subclinical atherosclerosis.
BACKGROUND Data on the relations of different types of fish meals and long-chain n-3 polyunsaturated fatty acids (PUFAs) to measures of atherosclerosis are sparse. OBJECTIVE We examined intakes of… Expand
Prediction of medical morbidity and mortality after acute myocardial infarction in patients at increased psychosocial risk in the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) study.
BACKGROUND Patients with myocardial infarction (MI) are at further increased risk for untoward events when patients also exhibit low social support and/or depression. The ENRICHD study was the… Expand
Prediction and prevention of transplant-related mortality from pulmonary causes after total body irradiation and allogeneic stem cell transplantation.
- B. Savani, A. Montero, +6 authors A. Barrett
- Biology of blood and marrow transplantation…
- 1 March 2005
Between July 1997 and August 2004, 146 consecutive patients with hematologic malignancies received a T cell-depleted peripheral blood stem cell transplant from an HLA-identical sibling by using total… Expand
Ankle-brachial index and subclinical cardiac and carotid disease: the multi-ethnic study of atherosclerosis.
The authors studied associations between ankle-brachial index (ABI) and subclinical atherosclerosis in the Multi-Ethnic Study of Atherosclerosis. Participants included 3,458 women (average age = 62.6… Expand
Cavernous carotid artery calcification and white matter ischemia.
- L. Babiarz, D. Yousem, B. Wasserman, C. Wu, W. Bilker, N. Beauchamp
- AJNR. American journal of neuroradiology
- 1 May 2003
BACKGROUND AND PURPOSE The relevance of cavernous carotid artery calcification on unenhanced CT scans of the brain has recently been investigated against the backdrop of the widespread implementation… Expand
The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay
- Karole N. D’Orazio, C. Wu, N. K. Sinha, Raphael Loll-Krippleber, G. Brown, R. Green
- Medicine, Biology
- 20 June 2019
Translation of problematic sequences in mRNAs leads to ribosome collisions that trigger a series of quality control events including ribosome rescue, degradation of the stalled nascent polypeptide,… Expand