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Nothing tastes as good as skinny feels: the neurobiology of anorexia nervosa
Individuals with anorexia nervosa (AN) engage in relentless restrictive eating and often become severely emaciated. Because there are no proven treatments, AN has high rates of relapse, chronicity,Expand
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Functional MRI of Language in Aphasia: A Review of the Literature and the Methodological Challenges
Animal analogue studies show that damaged adult brains reorganize to accommodate compromised functions. In the human arena, functional magnetic resonance imaging (fMRI) and other functionalExpand
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Age-related changes in word retrieval: Role of bilateral frontal and subcortical networks
Healthy older adults frequently report word-finding difficulties, yet the underlying cause of these problems is not well understood. This study examined whether age-related changes in word retrievalExpand
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Quantification of five neuropsychological approaches to defining mild cognitive impairment.
  • A. Jak, M. Bondi, +4 authors D. Delis
  • Medicine, Psychology
  • The American journal of geriatric psychiatry…
  • 1 May 2009
OBJECTIVES Operational definitions of cognitive impairment have varied widely in diagnosing mild cognitive impairment (MCI). Identifying clinical subtypes of MCI has further challenged diagnosticExpand
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Role of the Right and Left Hemispheres in Recovery of Function during Treatment of Intention in Aphasia
Two patients with residual nonfluent aphasia after ischemic stroke received an intention treatment that was designed to shift intention and language production mechanisms from the frontal lobe of theExpand
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Decreased white matter integrity in late-myelinating fiber pathways in Alzheimer's disease supports retrogenesis
The retrogenesis model of Alzheimer's disease (AD) posits that white matter (WM) degeneration follows a pattern that is the reverse of myelogenesis. Using diffusion tensor imaging (DTI) to test thisExpand
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Are Extremes of Consumption in Eating Disorders Related to an Altered Balance between Reward and Inhibition?
The primary defining characteristic of a diagnosis of an eating disorder (ED) is the “disturbance of eating or eating-related behavior that results in the altered consumption or absorption of food”Expand
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Left and right basal ganglia and frontal activity during language generation: contributions to lexical, semantic, and phonological processes.
fMRI was used to determine the frontal, basal ganglia, and thalamic structures engaged by three facets of language generation: lexical status of generated items, the use of semantic vs. phonologicalExpand
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Hunger Does Not Motivate Reward in Women Remitted from Anorexia Nervosa
BACKGROUND Hunger enhances sensitivity to reward, yet individuals with anorexia nervosa (AN) are not motivated to eat when starved. This study investigated brain response to rewards during hunger andExpand
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Processing Words with Emotional Connotation: An fMRI Study of Time Course and Laterality in Rostral Frontal and Retrosplenial Cortices
Responses of rostral frontal and retrosplenial cortices to the emotional significance of words were measured using functional magnetic resonance imaging (fMRI). Twenty-six strongly righthandedExpand
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