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Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment
We have recently identified the archaic cytokine macrophage migration inhibitory factor (MIF) as a non-canonical ligand of the CXC chemokine receptors CXCR2 and CXCR4 in inflammatory and atherogenicExpand
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Chemokines: Key Regulators of Mononuclear Cell Recruitment in Atherosclerotic Vascular Disease
Understanding the increasingly complex role of chemokines in various manifestations of atherosclerotic vascular disease and the apparent redundancy in their expression requires improved conceptsExpand
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Platelets and chemokines in atherosclerosis: partners in crime.
  • C. Weber
  • Medicine, Biology
  • Circulation research
  • 1 April 2005
It becomes increasingly evident that blood platelets do not only exert important functions in hemostasis and thrombus formation but are also involved in atherosclerotic vascular disease. A majorExpand
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Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10.
The chemokine RANTES has been implicated in neointimal hyperplasia after arterial injury. We analyzed the differential role of the RANTES receptors CCR1 and CCR5 by genetic deletion in apolipoproteinExpand
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Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation
Recent in vitro studies have suggested a role for sialylation in chemokine receptor binding to its ligand (Bannert, N., S. Craig, M. Farzan, D. Sogah, N.V. Santo, H. Choe, and J. Sodroski. 2001. J.Expand
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Crucial Role of the CCL2/CCR2 Axis in Neointimal Hyperplasia After Arterial Injury in Hyperlipidemic Mice Involves Early Monocyte Recruitment and CCL2 Presentation on Platelets
Monocyte chemoattractant protein-1 (also known as CC chemokine ligand 2 [CCL2]) and its receptor CC chemokine receptor 2 (CCR2) play a central role in the inflammatory response and neointimalExpand
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MicroRNAs in arterial remodelling, inflammation and atherosclerosis.
Atherosclerosis is now widely appreciated to represent a chronic inflammatory reaction of the vascular wall in response to dyslipidemia and endothelial distress involving the inflammatory recruitmentExpand
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Ccr1 deficiency reduces inflammatory remodelling and preserves left ventricular function after myocardial infarction
Myocardial necrosis triggers inflammatory changes and a complex cytokine cascade that are only incompletely understood. The chemokine receptor CCR1 mediates inflammatory recruitment in response toExpand
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Major trauma in winter sports: an international trauma database analysis
PurposeThe aim of this study was to compare the demographics, injury patterns, and outcomes following major trauma between Alpine skiing, snowboarding, and sledding winter sports.MethodsAnExpand
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Fracture of the lesser trochanter as a sign of undiagnosed tumor disease in adults
Isolated avulsion fractures of the pelvic ring are rare and occur predominantly in adolescent athletes. Isolated fractures of the lesser trochanter are reported to be pathognomic for tumor diseasesExpand
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