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In vitro differentiation of endothelial cells from AC133-positive progenitor cells.
TLDR
It is reported that human AC133(+) cells from granulocyte colony-stimulating factor-mobilized peripheral blood have the capacity to differentiate into endothelial cells (ECs) and in mice with severe combined immunodeficiency, AC133-derived cells form new blood vessels in vivo when injected subcutaneously together with A549 lung cancer cells. Expand
Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction.
TLDR
It is concluded that PCR amplification of CEA mRNA may lead to an earlier diagnosis of micrometastatic bone disease in patients with CEA-expressing carcinomas. Expand
Redefined nomenclature for members of the carcinoembryonic antigen family.
CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease.
TLDR
Expression of the cell adhesion molecule CEACAM1 in the primary tumors in melanoma patients is associated with the subsequent development of metastatic disease, raising the possibility of a functional role for this cellAdhesion molecule in the metastatic spread it indicates. Expand
CEA-related cell adhesion molecule 1: a potent angiogenic factor and a major effector of vascular endothelial growth factor.
TLDR
Data suggest that CEACAM1 is a major effector of VEGF in the early microvessel formation and may be a target for the inhibition of tumor angiogenesis. Expand
In vitro differentiation of endothelial cells from AC133-positive progenitor cells
TLDR
It is reported that human AC133+ cells from granulocyte colony-stimulating factor–mobilized peripheral blood have the capacity to differentiate into endothelial cells (ECs) and in mice with severe combined immunodeficiency, AC133-derived cells form new blood vessels in vivo when injected subcutaneously together with A549 lung cancer cells. Expand
Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomas.
TLDR
Findings indicate that the loss or reduced expression of the adhesion molecule BGP is a major event in colorectal carcinogenesis. Expand
Binding of Escherichia coli and Salmonella strains to members of the carcinoembryonic antigen family: differential binding inhibition by aromatic alpha-glycosides of mannose
TLDR
The results indicate that glycoproteins of the CEA family may be involved in the recognition of bacteria and the regulation of bacterial colonization on the basis of the distribution of CEA-like glycoprotein in tissues and body fluids. Expand
Methods for detection of point mutations: performance and quality assessment. IFCC Scientific Division, Committee on Molecular Biology Techniques.
TLDR
An overview of current methods for the detection of point mutations as well as small insertions and deletions in clinical diagnostics and the potential for standardization and automation is given. Expand
Immunocytological detection of micrometastatic cells: Comparative evaluation of findings in the peritoneal cavity and the bone marrow of gastric, colorectal and pancreatic cancer patients
TLDR
Using immunocytology, the peritoneal cavity and the bone marrow of 147 patients with gastric, colorectal and pancreatic cancer for micrometastatic cells was investigated and monoclonal antibodies against tumor‐associated antigens (TAA) were analyzed. Expand
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