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Abnormal sensitization and temporal summation of second pain (wind-up) in patients with fibromyalgia syndrome
&NA; Although individuals with fibromyalgia syndrome (FMS) consistently report wide‐spread pain, clear evidence of structural abnormalities or other sources of chronic stimulation of pain afferentsExpand
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Diffuse noxious inhibitory controls (DNIC) attenuate temporal summation of second pain in normal males but not in normal females or fibromyalgia patients
&NA; Diffuse noxious inhibitory control (DNIC) is part of a central pain modulatory system that relies on spinal and supraspinal mechanisms. Previous studies have shown that fibromyalgia (FMS)Expand
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Characteristics of temporal summation of second pain sensations elicited by brief contact of glabrous skin by a preheated thermode.
Temporal summation of sensory intensity was investigated in normal subjects using novel methods of thermal stimulation. A Peltier thermode was heated and then applied in a series of brief (700 ms)Expand
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Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome
&NA; Individuals diagnosed with fibromyalgia syndrome (FMS) report chronic pain that is frequently worsened by physical activity and improved by rest. Palpation of muscle and tendinous structuresExpand
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Anterior parietal cortical response to tactile and skin-heating stimuli applied to the same skin site.
1. The response of anterior parietal cortex to skin stimuli was evaluated with optical intrinsic signal imaging and extracellular microelectrode recording methods in anesthetized squirrel monkeys. 2.Expand
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Mechanisms underlying development of spatially distributed chronic pain (fibromyalgia)
Abstract Chronic fibromyalgia (FM) pain is prevalent (estimated as high as 13%), predominantly affects women, and is associated with a variety of focal pain conditions. Ongoing FM pain is referred toExpand
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An operant assay of thermal pain in conscious, unrestrained rats
Methods are described which provide quantification of learned operant and innate reflex responses to a thermal stimulus (heat or cold) and provide matched motor controls. The apparati and proceduresExpand
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Response of anterior parietal cortex to different modes of same-site skin stimulation.
Response of anterior parietal cortex to different modes of same-site skin stimulation. J. Neurophysiol. 80: 3272-3283, 1998. Intrinsic optical signal (IOS) imaging was used to study responses of theExpand
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Cues Supporting Recognition of the Orientation or Direction of Movement of Tactile Stimuli
In a previous investigation of human subjects with stimulation of the volar surface of the forearm (Jones and Vierck, 1973), it was shown that discrimination of line lengths is quite good, relativeExpand
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Enhanced temporal summation of second pain and its central modulation in fibromyalgia patients
&NA; We have previously shown that fibromyalgia (FMS) patients have enhanced temporal summation (windup) and prolonged decay of heat‐induced second pain in comparison to control subjects, consistentExpand
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