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Comparison of tests used to distinguish smokers from nonsmokers.
TLDR
It is concluded that cotinine is the measure of choice, but for most clinical applications carbon monoxide provides an acceptable degree of discrimination and is considerably cheaper and simpler to apply. Expand
Biochemical markers of smoke absorption and self reported exposure to passive smoking.
TLDR
The data indicate that cotinine provides a valid marker of the dose received from passive smoke exposure, and the non-invasive samples of urine and saliva are particularly suited to epidemiological investigations. Expand
Long-term switching to low-tar low-nicotine cigarettes.
TLDR
Puffing patterns and blood measures of smoke intake were studied in 12 subjects before and after switching to low-tar (10.9 mg) low-nicotine (0.7 mg) cigarettes for 12 weeks suggesting that subjects compensated to some extent by increasing inhalation. Expand
Effect of transdermal nicotine patches on cigarette smoking: a double blind crossover study
TLDR
It is suggested that the continuous absorption of nicotine from the patch may cause a build-up of acute tolerance to both toxic and pleasant subjective effects from smoking. Expand
Acute poisoning with gold cyanide
TLDR
A case of deliberate ingest ion of an electroplating solution containing gold cyanide with sublethal cyanide and high red blood cell gold levels suggest acute gold toxicity as the most likely cause of death. Expand
Cyanide and thiocyanate concentrations following sodium nitroprusside infusion in man.
TLDR
It is believed that the development of metabolic acidosis, and the recent fatalities involving SNP, are attributable to histotoxic hypoxia as a result of excessive plasma concentrations of cyanide. Expand
Low cost carbon monoxide monitors in smoking assessment.
TLDR
Results from two carbon 60 * 0 monoxide monitors costing less than £400 have become available and are compared with results from the standard expired air carbon monoxide monitor (Ecolyzer 2000) and with blood 20 carboxyhaemoglobin concentrations. Expand
Blood cyanide and thiocyanate concentrations produced by long-term therapy with sodium nitroprusside.
TLDR
It is suggested that, to avoid SCN toxicity (plasma SCN greater than 1.75 mumol litre-1), in the absence of SCN monitoring, the total SNP dose should be less than 70 mg kg-1 in patients with normal renal function. Expand
Some Metabolic Effects of Sodium Nitroprusside in Man
TLDR
The infusion of sodium nitroprusside during surgical operations produced plasma levels of cyanide of up to four times the control value, and the ratio of methylcobalamin to adenosyl + hydroxocobalamin fell and cyanocobalamins concentrations were high. Expand
Carboxyhaemoglobin and plasma thiocyanate: complementary indicators of smoking behaviour?
TLDR
It is concluded that in this study determination of thiocyanate added little to the information obtained from carboxyhaemoglobin measurements alone, and statistical combination of the carboxYhaemobic results, with the use of linear discrimination analysis, only marginally improved their diagnostic efficiency. Expand
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