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Problems and progress in the diagnosis and treatment of polydipsia and hyponatremia.
Fluid-electrolyte balance is regulated within a narrow range and disturbances in this system are unusual in animals and humans. Studies from the preneuroleptic era to date suggest that up to 25Expand
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Clozapine withdrawal effects and receptor profiles of typical and atypical neuroleptics
Withdrawal effects of neuroleptics have not received much attention. Clozapine withdrawal phenomena have been attributed to psychosis arising from D2 supersensitivity, which is unlikely since it hasExpand
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Rapid high-performance liquid chromatographic method for the measurement of atenolol in plasma using UV detection.
A rapid, selective and reproducible high-performance liquid chromatographic method has been developed for the measurement of the beta-adrenoceptor blocking drug atenolol in small (400 microliters)Expand
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Pirmenol kinetics and effective oral dose
The oral form of pirmenol has not been administered to man. Pirmenol was given by mouth to eight patients with chronic, stable premature ventricular beats (PVBs) to determine effective dose andExpand
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Efficacy, safety, and pharmacokinetics of a concentration-maintaining regimen of intravenous pirmenol.
A 3-stage, concentration-maintaining intravenous infusion regimen of pirmenol, a new antiarrhythmic agent, was tested for efficacy and safety in 8 subjects with chronic, stable premature ventricularExpand
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Pharmacokinetics of neuroleptics.
Older studies on neuroleptic pharmacokinetics had problems in methodology and laboratory techniques. High performance liquid chromatography (HPLC) and combinations of techniques are used now.Expand
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Nicotine addiction in chronic schizophrenic inpatients
27) were adult neuroleptic-medicated inpatients with a DSM-III-R diagnosis of chronic schizophrenia (n = 22) or schizoaffective disorder (n = 5). Paired t tests revealed higher B! than NAARTExpand
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The evaluation of domperidone and metoclopramide as antiemetics in day care abortion patients.
A randomised double-blind investigation was undertaken to assess the value of domperidone and metoclopramide as prophylactic anti-emetics in unpremedicated patients undergoing general anaesthesia forExpand
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