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Pluripotency of mesenchymal stem cells derived from adult marrow
TLDR
This corrects the article to say that the author of the paper was a post-graduate student at the Massachusetts Institute of Technology (MIT) when he wrote the paper, not a scientist. Expand
Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells.
TLDR
MPCs that proliferate without obvious senescence under clinically applicable conditions and differentiate at the single-cell level not only into mesenchymal cells but also cells of visceral mesoderm may be an ideal source of stem cells for treatment of genetic or degenerative disorders affecting cells of mesodermal origin. Expand
Origin of endothelial progenitors in human postnatal bone marrow.
TLDR
Because MAPCs can be expanded in culture without obvious senescence for more than 80 population doublings, they may be an important source of endothelial cells for cellular pro- or anti-angiogenic therapies. Expand
Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain.
TLDR
This study shows that cells with MAPC characteristics can be isolated not only from BM, but also from brain and muscle tissue. Expand
Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells.
TLDR
MAPCs, derived from normal human, mouse, and rat postnatal bone marrow primitive, multipotent adult progenitor cells, can differentiate into cells with morphological, phenotypic, and functional characteristics of hepatocytes, and may be an ideal cell for in vivo therapies for liver disorders or for use in bioartificial liver devices. Expand
Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy.
TLDR
Patients with high-risk hematologic malignancy received 2 partially HLA-matched UCB units and disease-free survival was 57% at 1 year, with 72% of patients alive if they received transplants while in remission. Expand
Pluripotency of mesenchymal stem cells derived from adult marrow
We report here that cells co-purifying with mesenchymal stem cells—termed here multipotent adult progenitor cells or MAPCs—differentiate, at the single cell level, not only into mesenchymal cells,Expand
Neuroectodermal differentiation from mouse multipotent adult progenitor cells
TLDR
Mouse (m)MAPCs differentiate into mesenchymal lineage cells as well as endothelium and endoderm, and, when injected in the blastocyst, mMAPCs contribute to most if not all somatic cell lineages including the different cell types of the brain. Expand
Stem cells for ischemic brain injury: A critical review
TLDR
Evidence to date suggests that continued development of stem cell therapies may ultimately lead to viable treatment options for ischemic brain injury, and careful investigation of the mechanisms underlying trophic benefits will be essential. Expand
Mesenchymal Stem Cells Migration Homing and Tracking
TLDR
This review discusses the migration and homing ability of mesenchymal stem cells (MSCs) and MSC-like cells and factors influencing this and the different methods available and frequently used to track and identify the injected cells in vivo. Expand
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