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A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy.
- A. Dirksen, J. Dijkman, +13 authors J. Stolk
- American journal of respiratory and critical care…
- 1 November 1999
We have investigated whether restoration of the balance between neutrophil elastase and its inhibitor, alpha(1)-antitrypsin, can prevent the progression of pulmonary emphysema in patients with… Expand
Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression
- G. Gudmundsson, T. Gislason, +7 authors P. Bakke
- European Respiratory Journal
- 1 September 2005
The aim of the present study was to analyse the risk of rehospitalisation in patients with chronic obstructive pulmonary disease and associated risk factors. This prospective study included 416… Expand
Occupational chronic obstructive pulmonary disease: a systematic literature review.
OBJECTIVE Occupational-attributable chronic obstructive pulmonary disease (COPD) presents a substantial health challenge. Focusing on spirometric criteria for airflow obstruction, this review of… Expand
Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity
BackgroundThe aim of this study was to analyse mortality and associated risk factors, with special emphasis on health status, medications and co-morbidity, in patients with chronic obstructive… Expand
Decline of lung function in adults with bronchial asthma.
To investigate the annual decline of lung function in subjects with self-reported asthma, we analyzed data from a longitudinal epidemiologic study. The Copenhagen City Heart Study. The study sample… Expand
The Patient's Perspective: Adherence or Non-adherence to Asthma Controller Therapy?
- C. Ulrik, V. Backer, U. Søes-Petersen, P. Lange, H. Harving, Peter P Plaschke
- The Journal of asthma : official journal of the…
- 1 January 2006
Study objective. Adherence with controller therapy poses a major challenge to the effective management of persistent asthma. The aim of this study was to explore the patient-related aspects of… Expand
Nonreversible airflow obstruction in life-long nonsmokers with moderate to severe asthma.
The aim of this longitudinal study was to assess the frequency of nonreversible airflow obstruction (NRAO) among adults with moderate to severe asthma, and to compare the decline of forced expiratory… Expand
Mortality and markers of risk of asthma death among 1,075 outpatients with asthma.
BACKGROUND According to national health statistics, mortality rates for asthma have been increasing steadily over the past decades. Mortality and markers of risk of death from asthma were studied… Expand
Atopy in Danish children and adolescents: results from a longitudinal population study.
BACKGROUND AND OBJECTIVE Atopy is an objectively measurable trait related to the presence of rhinitis and asthma, but our knowledge about its longitudinal predictors is limited. Data from a 6-year… Expand
Once-daily glycopyrronium bromide, a long-acting muscarinic antagonist, for chronic obstructive pulmonary disease: a systematic review of clinical benefit
- C. Ulrik
- International journal of chronic obstructive…
- 26 September 2012
Background: Long-acting bronchodilators are central in the pharmacological management of patients with chronic obstructive pulmonary disease (COPD). The aim of this systematic review is to provide an… Expand