Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
CD44 exhibits a cell type dependent interaction with triton X-100 insoluble, lipid rich, plasma membrane domains.
- S. Neame, C. Uff, H. Sheikh, S. Wheatley, C. Isacke
- Biology, Medicine
- Journal of cell science
- 1 September 1995
Evidence is presented that the detergent insolubility of fibroblast CD44 at 4 degrees C results from an association of the CD44 transmembrane domain with Triton X-100 resistant, lipid rich, plasma membrane domains. Expand
Influence of soluble suture factors on in vitro macrophage function.
It is demonstrated that sutures release immunotoxic factors which considerably influence macrophage behaviour in vitro, which may have important clinical implications. Expand
PACE-1, a novel protein that interacts with the C-terminal domain of ezrin.
The identification and cloning of a novel protein, PACE-1, which binds to the C-terminal domain of ezrin is described, suggesting that Pace-1 may play a role in regulating cell adhesion/migration complexes in migrating cells. Expand
Hyaluronan binding by CD44 is regulated by a phosphorylation‐independent mechanism
In transfected AKR1 cells the behavior of both the neutral and acidic mutants was indistinguishable from wild‐type CD44, indicating that there is a phosphorylation‐independent mechanism involved in regulating hyaluronan binding. Expand
CD44 EXPRESSION IN REJECTING RAT SMALL BOWEL ALLOGRAFTS1,2
The findings indicate the involvement of CD44 in the rejection process and demonstrate changes in the proliferative profile of rejecting small intestinal epithelium. Expand
Effect of suture material on tumour cell adherence at sites of colonic injury
Tumour cell adherence at sites of colonic injury is dependent on the suture material used and not on the injury itself in this model, which may be important when choosing suture type for anastomosis in patients undergoing surgery for colorectal cancer. Expand
DIFFERENTIAL EXPRESSION OF ADHESION MOLECULES DURING RAT SMALL BOWEL ALLOGRAFT REJECTION
- S. Reid, C. Uff, I. Saeed, J. Ross, R. Wood, A. Pockley
- Biology, Medicine
- 1 November 1995
It is suggested that adhesion molecules are involved in the development and progression of allograft rejection and may present suitable targets for immunotherapeutic protocols after small bowel transplantation. Expand
Experimental carcinogenesis at sutured and sutureless colonic anastomoses
All sutures seem to enhance anastomotic tumor formation, and it is suggested that a suturelessAnastomosis may diminish this risk. Expand
Suppression of macrophage function by suture materials and anastomotic recurrence of Crohn's disease
After surgical excision of bowel, Crohn's disease is likely to recur around the anastomosis. It is suggested that this may indicate a biological effect of suture materials on gastrointestinal… Expand
A rapid microplate-based fluorometric assay for phagocytosis.
A highly sensitive quantitative fluorometric assay for phagocytosis, previously measured using fluorescence spectrophotometry or flow cytometry, has been adapted for use with a 96-well fluorescence… Expand