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Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human.
TLDR
The ratio of nonsynonymous/synonymous nucleotide substitution in palm civets collected 1 yr apart from different geographic locations is very high, suggesting a rapid evolving process of viral proteins in civet as well, much like their adaptation in the human host in the early 2002-2003 epidemic. Expand
Antibodies to SARS Coronavirus in Civets
TLDR
Using three different assays, serum samples collected from different civet farms and a market in China in June 2003 and January 2004 suggest no widespread infection among civets resident on farms, and the infection of cvets in the market might be associated with trading activities under the conditions of overcrowding and mixing of various animal species. Expand
Phylogenetic comparison of classical swine fever virus in China.
TLDR
Results indicated that CSF viruses predominating in recent epizootics within China are genetically divergent from the reference strain Shimen and the vaccine strain HCLV. Expand
Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia
TLDR
Molecular and serological evidence of SARS-CoV-2 related coronaviruses (SC2r-CoVs) actively circulating in bats in Southeast Asia are reported and the geographic distribution of genetically diverse SC2r -CoVs from Japan and China to Thailand over a 4800-km range is extended. Expand
Identification of Diverse Alphacoronaviruses and Genomic Characterization of a Novel Severe Acute Respiratory Syndrome-Like Coronavirus from Bats in China
TLDR
Diverse alphacoronaviruses and a close relative (LYRa11) to SARS CoV are identified in bats collected in Yunnan, China, indicating that most reported bat SARS-like CoVs are not the progenitors of human Sars CoV. Expand
Pivotal Role of Dogs in Rabies Transmission, China
TLDR
This work reviews the incidence of rabies in China based on data from 1950 and 2004, obtained mainly from epidemiologic bulletins published by the Chinese Ministry of Health. Expand
Civets Are Equally Susceptible to Experimental Infection by Two Different Severe Acute Respiratory Syndrome Coronavirus Isolates
TLDR
It is shown that civets were equally susceptible to SARS-CoV isolates GZ01 and BJ01, and the infection was confirmed by virus isolation, detection of viral genomic RNA, and serum-neutralizing antibodies. Expand
Challenges and needs for China to eliminate rabies
TLDR
In conclusion, strategic planning is needed to provide a sense of direction, demonstrate feasibility of elimination in China, and develop a research agenda, addressing country’s operational needs and constraints. Expand
Xi River virus, a new bat reovirus isolated in southern China
TLDR
A putative sixth member of the Orthoreovirus family, Xi River virus, isolated from fruit bats collected in a location near the Xi River, Guangdong Province, China, showed the same electron microscopic morphology as NBV, fusogenic CPE, and a 10-segmented double-strand RNA genome, as well as high sequence identity to NBV members. Expand
Evaluation of a multiplex real-time RT-PCR for quantitative and differential detection of wild-type viruses and C-strain vaccine of Classical swine fever virus.
TLDR
The multiplex real-time RT-PCR was able to detect the viral RNA in the whole blood samples of experimentally infected pigs as early as 2 days post-infection, 3 to 4 days prior to the onset of clinical signs in co-housed pigs, and completely correct differentiation of wild-type viruses from C-strain vaccine in China. Expand
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