Endocrinology of the stress response.
- E. Charmandari, C. Tsigos, G. Chrousos
- Biology, MedicineAnnual Review of Physiology
- 2005
The stress response is subserved by the stress system, which is located both in the central nervous system and the periphery. The principal effectors of the stress system include…
Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress.
- C. Tsigos, G. Chrousos
- Biology, MedicineJournal of Psychosomatic Research
- 1 October 2002
European Guidelines for Obesity Management in Adults
It is concluded that physicians have a responsibility to recognise obesity as a disease and help obese patients with appropriate prevention and treatment and focus on realistic goals and lifelong multidisciplinary management.
Management of Obesity in Adults: European Clinical Practice Guidelines
- C. Tsigos, V. Hainer, B. Zahorska‐Markiewicz
- MedicineObesity Facts
- 18 April 2008
Doctors have a responsibility to recognise obesity as a disease and help obese patients with appropriate prevention and treatment, and treatment should be based on good clinical care and evidence-based interventions and obesity treatment should focus on realistic goals and lifelong management.
Prevalence, Pathophysiology, Health Consequences and Treatment Options of Obesity in the Elderly: A Guideline
- E. Mathus-Vliegen, A. Basdevant, B. Zahorska‐Markiewicz
- MedicineObesity Facts
- 1 June 2012
Life-style intervention should be the first step and consists of a diet with a 500 kcal (2.1 MJ) energy deficit and an adequate intake of protein of high biological quality together with calcium and vitamin D, behavioural therapy and multi-component exercise.
High‐dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia
- Kristine A. Nelson, Karen M. Park, E. Robinovitz, C. Tsigos, M. Max
- Medicine, PsychologyNeurology
- 1 May 1997
It is concluded that dextromethorphan or other low-affinity NMDA channel blockers may have promise in the treatment of painful diabetic neuropathy.
Stress, Visceral Obesity, and Metabolic Complications
- I. Kyrou, G. Chrousos, C. Tsigos
- BiologyAnnals of the New York Academy of Sciences
- 1 November 2006
The physiology of the stress system response is described, with emphasis on metabolism, and the recent data that implicate several neuroendocrine and inflammatory mechanisms mobilized during chronic stress in the development of the metabolic complications that characterize central obesity and the metabolic syndrome are reviewed.
Brief report: testicular and ovarian resistance to luteinizing hormone caused by inactivating mutations of the luteinizing hormone-receptor gene.
- A. Latronico, J. Anasti, G. Chrousos
- BiologyNew England Journal of Medicine
- 1 July 1996
The maternal hypothalamic–pituitary–adrenal axis in the third trimester of human pregnancy
- M. Magiakou, G. Mastorakos, G. Chrousos
- Biology, MedicineClinical Endocrinology
- 1 April 1996
OBJECTIVE The third trimester of pregnancy is characterized by a mildly hyperactive hypothalamic–pituitary–adrenal (HPA) axis, possibly driven by elevated circulating levels of corticotrophin…
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