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Effect of an angiotensin II receptor blocker and two angiotensin converting enzyme inhibitors on transforming growth factor-beta (TGF-beta) and alpha-actomyosin (alpha SMA), important mediators of
TLDR
The finding that ACE inhibitors or ANG II receptor blockers protect the lungs from radiation induced pneumonitis and fibrosis reaffirms the role that ANG II plays in this inflammatory process and suggests an additional indication of treatment of this condition, thus opening a new potential pharmacologic use of these drugs. Expand
Relations between sweating, cutaneous blood flow, and body temperature in work.
TLDR
Finger and mean skin temperatures decreased at the beginning of work, and men worked on a treadmill for periods of 5, 5, 10, 10 and 10 min, stopping for 2 min between work periods to be weighed. Expand
Effect of an angiotensin II receptor blocker and two angiotensin converting enzyme inhibitors on transforming growth factor-β (TGF-β) and α-actomyosin (α SMA), important mediators of
TLDR
The finding that ACE inhibitors or ANG II receptor blockers protect the lungs from radiation induced pneumonitis and fibrosis reaffirms the role that ANG II plays in this inflammatory process and suggests an additional indication of treatment of this condition, thus opening a new potential pharmacologic use of these drugs. Expand
Stability of plasma for add-on PT and APTT tests.
TLDR
Research found that the PT of the majority of plasma samples from healthy subjects and from patients receiving oral anticoagulant therapy tended to become shorter on storage, and add-on tests for PT and APTT could be performed with results similar to what would be obtained from testing unstored samples. Expand
Radiation injury in rat lung. I. Prostacyclin (PGI2) production, arterial perfusion, and ultrastructure.
Pulmonary prostacyclin (PGI2) production, arterial perfusion, and ultrastructure were correlated in rats sacrificed from 1 day to 6 months after a single exposure of 25 Gy of gamma rays to the rightExpand
Captopril reduces collagen and mast cell accumulation in irradiated rat lung.
TLDR
These data are the first to demonstrate that the ACE inhibitor captopril might provide a novel intervention in the pathogenesis of radiation fibrosis. Expand
Prostacyclin synthesis in irradiated endothelial cells cultured from bovine aorta.
TLDR
There was an increased platelet interaction with irradiated monolayers, as a result of platelet adherence to subendothelial matrix exposed after cell detachment, however, irradiation did not alter the nonadherent property of the endothelial cell surface toward platelets. Expand
Basal endothelial attachment. Tenacity at cytoplasmic dense zones in the rabbit aorta.
  • C. Ts'ao, S. Glagov
  • Biology, Medicine
  • Laboratory investigation; a journal of technical…
  • 1 November 1970
Effect of an Aortic Proteoglycan on Platelet Aggregation and Thrombin Time: Plasma Requirement and Active Moieties 1
TLDR
The location of the bovine aortic proteoglycan in the arterial wall and its antithrombic activity suggest it plays a role in regulating the response of the circulating blood to vascular injury. Expand
Radiation pneumotoxicity in rats: modification by inhibitors of angiotensin converting enzyme.
TLDR
A novel application for ACE inhibitors in general, and for Captopril in particular, as modifiers of radiation pneumotoxicity are suggested. Expand
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