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Effect of a local anesthetic lozenge in relief of symptoms in burning mouth syndrome.
TLDR
The results indicate that the bupivacaine lozenge offers a novel therapeutic modality to patients with BMS, although without alleviating effect on the associated symptoms, taste alterations, and xerostomia.
New lidocaine lozenge as topical anesthesia compared to lidocaine viscous oral solution before upper gastrointestinal endoscopy
TLDR
The lozenge reduced the gag reflex, diminished patients’ discomfort during UGE, and was evaluated as having a good taste and texture.
Absorption of Bupivacaine after Administration of a Lozenge as Topical Treatment for Pain from Oral Mucositis
TLDR
Simulations showed that the plasma concentrations would be below the toxic limit after repeated dosing every second hour with 25 mg bupivacaine for five days, based on PK simulations of repeated doses of 25 mg every two hours for 16 hr a day, the lozenges can be administered with minimum risk of exceeding the toxiclimit.
Kidney function estimates using cystatin C versus creatinine: Impact on medication prescribing in acutely hospitalized elderly patients
TLDR
Differences between estimated glomerular filtration rate (eGFR) based on creatinine and cystatin C and how these differences would affect prescribing recommendations among acutely hospitalized elderly patients are investigated.
A Collaborative Medication Review Including Deprescribing for Older Patients in an Emergency Department: A Longitudinal Feasibility Study
TLDR
A collaborative medication review and deprescribing intervention is feasible to perform in the emergency department of older medical patients using polypharmacy using polyPharmacy (≥5 long-term medications).
Creatinine-Based Renal Function Estimates and Dosage of Postoperative Pain Management for Elderly Acute Hip Fracture Patients
TLDR
Differences between creatinine-based eGFR equations and how the choice of equation influences dosage of analgesics in elderly (≥70 years) patients admitted with acute hip fracture are investigated.
Discrepancies Between the Medication List in Electronic Prescribing Systems and Patients' Actual Use of Medicines.
TLDR
The aim of this study was to evaluate the number and types of discrepancies between medications listed in the SMR and an updated medication list, obtained through a thorough medication reconciliation, for patients admitted in Danish hospitals, and shows that theSMR should not be used as the only source of information when recording medication history.
One-Stop Dispensing: Hospital Costs and Patient Perspectives on Self-Management of Medication
TLDR
There were no differences in medication costs, but staff time was significantly lower in OSD and patients were overall satisfied with OSD.
Differences in Kidney Function Estimates Based on Creatinine and/or Cystatin C in Non-Traumatic Amputation Patients and Their Impact on Drug Prescribing
TLDR
Investigation of how amputation affects estimated glomerular filtration rate (eGFR) and if dosing recommendations differ among different eGFR equations found no differences among equations, which would impact prescribing of renally-eliminated medications.
Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy: A Randomized, Controlled Trial
TLDR
A bupivacaine lozenge compared with a lidocaine spray proved to be a superior option as topical pharyngeal anesthetic before an UGE.
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