The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population
FLI is simple to obtain and may help physicians select subjects for liver ultrasonography and intensified lifestyle counseling, and researchers to select patients for epidemiologic studies, but validation of FLI in external populations is needed before it can be employed for these purposes.
A new definition for metabolic associated fatty liver disease: an international expert consensus statement.
Prevalence of and risk factors for nonalcoholic fatty liver disease: The Dionysos nutrition and liver study
- G. Bedogni, L. Miglioli, F. Masutti, C. Tiribelli, G. Marchesini, S. Bellentani
- 1 July 2005
NAFLD is highly prevalent in the general population, is not associated with SLD, but is associated with many features of the metabolic syndrome.
Prevalence of and Risk Factors for Hepatic Steatosis in Northern Italy
Data indicate that obesity plays a greater role than excessive alcohol intake in inducing fatty liver, and the relative roles of obesity and alcohol abuse, alone and in combination, in inducing steatosis are explored.
Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis.
The many functions of APE1/Ref-1: not only a DNA repair enzyme.
- G. Tell, F. Quadrifoglio, C. Tiribelli, M. Kelley
- BiologyAntioxidants and Redox Signaling
- 1 March 2009
The most relevant information concerning APE1's different functions are attempted to coalesce in order to shed new light and to focus current and future studies to fully understand this unique molecule that is acquiring more and more interest and translational relevance in the field of molecular medicine.
Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection.
Clear evidence is provided that occult HBV is a risk factor for development of HCC and that the potential mechanisms whereby overt HBV might induce tumor formation are mostly maintained in cases of occult infection.
Clinical patterns of hepatocellular carcinoma in nonalcoholic fatty liver disease: A multicenter prospective study
NAFLD‐HCC is more often detected at a later tumor stage and could arise also in the absence of cirrhosis, but after patient matching, it has a similar survival rate compared to HCV infection; a future challenge will be to identify patients with NAFLD who require more stringent surveillance in order to offer the most timely and effective treatment.
A simple index of lipid overaccumulation is a good marker of liver steatosis
In a study sample of adults from Northern Italy, the simple calculation of LAP was a reasonably accurate approach to recognizing individuals with ultrasonographic liver steatosis.
Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis
- R. Longo, P. Pollesello, L. Dalla Palma
- Medicine, ChemistryJournal of Magnetic Resonance Imaging
- 1 May 1995
The results indicate that determination of the fat volume fraction in steatotic liver can be achieved noninvasively with MR spectroscopy.