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Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
TLDR
A draft genome sequence of the red jungle fowl, Gallus gallus, provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes.
A positive feedback loop coordinates growth and patterning in the vertebrate limb
TLDR
It is reported here that Fgf4 expression in the ridge can be regulated byshh-expressing cells, and Shh expression in mesenchyme can be activated by FGF4 in combination with retinoic acid, thus establishing a positive feedback loop between ZPA and ridge.
Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb.
TLDR
It is shown here that bone morphogenetic protein 2 (BMP-2) is involved in patterning the developing chick limb and there is a close relationship, both temporal and spatial, between the activation of the Bmp-2 and Hoxd-13 genes in response to retinoic acid and polarizing region grafts, suggesting that expression of the two genes might be linked.
Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning.
TLDR
It is shown that the feather tract is initiated by a continuous stripe of Shh, Fgf-4, and Ptc expression in the epithelium, which then segregates into discrete feather primordia that are more strongly Shh and FgF-4 positive.
Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb.
TLDR
The results argue that the dose-dependent effects of Shh in the regulation of anteroposterior pattern in the limb may be mediated by some other signal(s).
Developmental basis of limblessness and axial patterning in snakes
TLDR
It is shown that Hox gene expression domains are expanded along the body axis in python embryos, and that this can account for both the absence of forelimbs and the expansion of thoracic identity in the axial skeleton.
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