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Increased urinary 1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytidine excretion in thalassemia patients: markers for lipid peroxidation-induced DNA damage.
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Effect of green tea on iron status and oxidative stress in iron-loaded rats.
TLDR
Green tea extract can decrease iron in plasma as well as eliminate lipid peroxidation in plasma, and destroy formation of erythrocyte ROS in the rats challenged with iron.
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Curcumin contributes to in vitro removal of non-transferrin bound iron by deferiprone and desferrioxamine in thalassemic plasma.
TLDR
None of these chelators removed NTBI completely, but curcumin appeared to increase the rate of NTBI removal when added to DFP, and it is proposed that the beta-diketo moiety ofCurcumin participates in the NTBI chelation.
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Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress.
TLDR
EGCG and ECG could be natural iron chelators that efficiently decrease the levels of NTBI and free radicals in iron overload in beta-thalassemia patients.
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Reversal of cardiac iron loading and dysfunction in thalassemic mice by curcuminoids.
TLDR
Curcuminoids (CUR) can chelate plasma NTBI, inhibit lipid peroxidation and alleviate cardiac autonomic imbalance, and imply that CUR would be effective in decreasing plasma NT BI and myocardial iron, alleviating lipid per oxidation and improving cardiac function in iron-loaded thalassemic mice.
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Accumulation of lipid peroxidation‐derived DNA lesions in iron‐overloaded thalassemic mouse livers: Comparison with levels in the lymphocytes of thalassemia patients
TLDR
It is concluded that promutagenic LPO‐derived DNA lesions are involved in the onset of hepatocellular carcinoma in patients with thalassemia, and these patients have high levels of iron overload.
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Iron-Chelating and Free-Radical Scavenging Activities of Microwave-Processed Green Tea in Iron Overload
TLDR
Green tea crude extract time- and dose-dependently decreased plasma NTBI concentration and counteracted the increase of oxidative stress in both Fe 2+-EDTA-treated human plasma and erythrocytes.
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Efficacy of curcuminoids in alleviation of iron overload and lipid peroxidation in thalassemic mice.
TLDR
Curcuminoids is effective in chelation of plasma NTBI in iron-loaded thalassemic mice and can alleviate iron toxicity and harmfulness of free radicals, according to prospective investigation.
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Anti-oxidant properties and anti-hemolytic activity of Psidium guajava, Pandanous odorus and Rhinacanthus nasutus
The ethanolic extracts of leaves of Psidium guajava (PG), Pandanous odorus (PO),Rhinacanthus nasutus (RN) contained polyphenolic compounds in the order of PG > RN > PO. All the extracts exhibited…
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High prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates: A 5-year retrospective study at a Tertiary Hospital in Northern Thailand
Background The global emergence and spread of extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales, especially Escherichia coli and Klebsiella pneumoniae, have been recognized as a…
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