• Publications
  • Influence
VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
The specific role of VEGFA-induced permeability and vascular leakage in physiology and pathology has remained unclear. Here we show that VEGFA-induced vascular leakage depends on signalling initiatedExpand
  • 67
  • 4
  • PDF
NRP1 presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation.
Neuropilin 1 (NRP1) modulates angiogenesis by binding vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. We examined the consequences when VEGFR2 and NRP1 were expressed on the sameExpand
  • 74
  • 2
  • PDF
VEGF receptor‐2/neuropilin 1 trans‐complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival
Unstable and dysfunctional tumor vasculature promotes cancer progression and spread. Signal transduction by the pro‐angiogenic vascular endothelial growth factor (VEGF) receptor‐2 (VEGFR2) isExpand
  • 10
  • 2
  • PDF
Matrigel plug assay: evaluation of the angiogenic response by reverse transcription-quantitative PCR
The subcutaneous Matrigel plug assay in mice is a method of choice for the in vivo evaluation of pro- and anti-angiogenic molecules. However, quantification of the angiogenic response in the plugExpand
  • 13
  • 2
Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period
Rationale: Lymphatic vessels in the respiratory tract normally mature into a functional network during the neonatal period, but under some pathological conditions they can grow as enlarged, dilatedExpand
  • 41
  • 1
Matrigel plug assay: evaluation of the angiogenic response by reverse transcription-quantitative PCR
The subcutaneous Matrigel plug assay in mice is a method of choice for the in vivo evaluation of pro- and anti-angiogenic molecules. However, quantification of the angiogenic response in the plugExpand
  • 19
  • PDF
Glutamic-dehydrogenase activity inhibition by phenoxyacilic acids
SummaryExperiments were carried out on the effects of some phenoxyacilic acids, used as herbicides, on the glutamic-dehydrogenase (GLDH) activity.2,4-D,2,4,5-T, MCPA and Dichlorprop inhibited GLDHExpand
  • 2
Spectroscopic characterization of extracts from humic and fulvic fractions: IR and1H NMR spectra
SummaryInfrared and proton resonance spectra have been used to characterize fraction extracted sequentially from humic and fulvic acids by diethylether, acetone, dioxane, tetrahydrofuran, pyridineExpand
  • 9
Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2
Exaggerated signaling by vascular endothelial growth factor (VEGF)‐A and its receptor, VEGFR2, in pathologies results in poor vessel function. Still, pharmacological suppression of VEGFA/VEGFR2 mayExpand
  • 5