• Publications
  • Influence
Low Energy Shock Wave Therapy Induces Angiogenesis in Acute Hind-Limb Ischemia via VEGF Receptor 2 Phosphorylation
Objectives Low energy shock waves have been shown to induce angiogenesis, improve left ventricular ejection fraction and decrease angina symptoms in patients suffering from chronic ischemic heartExpand
  • 34
  • 1
  • PDF
Shock Wave Treatment Protects From Neuronal Degeneration via a Toll‐Like Receptor 3 Dependent Mechanism: Implications of a First‐Ever Causal Treatment for Ischemic Spinal Cord Injury
Background Paraplegia following spinal cord ischemia represents a devastating complication of both aortic surgery and endovascular aortic repair. Shock wave treatment was shown to induce angiogenesisExpand
  • 11
  • 1
  • PDF
Shock wave treatment induces angiogenesis and mobilizes endogenous CD31/CD34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis.
OBJECTIVES Shock waves have been shown to induce recruitment of intravenously injected endothelial progenitor cells to ischemic hind limbs in rats. We hypothesized that shock wave treatment as soleExpand
  • 72
  • PDF
Epicardial shock‐wave therapy improves ventricular function in a porcine model of ischaemic heart disease
Previously we have shown that epicardial shock‐wave therapy improves left ventricular ejection fraction (LVEF) in a rat model of myocardial infarction. In the present experiments we aimed to addressExpand
  • 24
Shockwave Therapy Differentially Stimulates Endothelial Cells: Implications on the Control of Inflammation via Toll-Like Receptor 3
Shock wave therapy (SWT) reportedly improves ventricular function in ischemic heart failure. Angiogenesis and inflammation modulatory effects were described. However, the mechanism remains largelyExpand
  • 40
  • PDF
Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle.
AIMS Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for the treatment of ischaemic heart or limb disease. Despite promising results inExpand
  • 29
  • PDF
Vein graft thrombi, a niche for smooth muscle cell colonization – a hypothesis to explain the asymmetry of intimal hyperplasia
Essentials Vein graft failure is the most frequent late onset complication of coronary artery bypass grafting. Cuff technique‐based interposition mouse model including new anticoagulation regime wasExpand
  • 13
Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice†.
OBJECTIVES Tissue-engineered xenografts represent a promising treatment option in heart valve disease. However, inflammatory response leading to graft failure and incomplete in vitro repopulationExpand
  • 12
Shockwaves prevent from heart failure after acute myocardial ischaemia via RNA/protein complexes
Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll‐like receptor 3 (TLR3). The antimicrobial peptide LL37 gets released by mechanical stress and is known toExpand
  • 7
  • PDF
Shock wave application to cell cultures.
Shock waves nowadays are well known for their regenerative effects. Basic research findings showed that shock waves do cause a biological stimulus to target cells or tissue without any subsequentExpand
  • 16
  • PDF