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Modulation of angiotensin II binding sites in neuronal cultures by mineralocorticoids.
TLDR
Observations suggest that the mineralocorticoid-induced increase in [125I]ANG II-specific binding in H/BS neuronal cultures is a specific event, which is mediated via mineraloc Corticoid type I receptors and which requires protein synthesis. Expand
Effect of chronic dietary treatment with L-tryptophan on the maintenance of hypertension in spontaneously hypertensive rats.
TLDR
It is shown that chronic dietary administration of tryptophan can reduce the elevated blood pressure of SH rats and support the possibility that this neutral amino acid may act via its effect on the concentration of the neurohormones, norepinephrine and dopamine, in the diencephalon to regulate the binding of Ang II to its receptors. Expand
Chronic dietary administration of tryptophan prevents the development of deoxycorticosterone acetate salt induced hypertension in rats.
TLDR
It is suggested that tryptophan provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats. Expand
Plasma catecholamines and their effect on blood lactate and muscle lactate output.
TLDR
It is concluded that E causes CaL to rise and that both E and NE increase maximal net lactate output during contractions. Expand
Effects of catecholamines on lactic acid output during progressive working contractions.
TLDR
The goal was to mimic, for in situ dog skeletal muscle, the concentrations of these catecholamines in the blood and the contractions during progressive exercise and suggest that E is more active than NE. Expand
Reduced dipsogenic responsiveness to intracerebroventricularly administered angiotensin II in estrogen-treated rats
TLDR
The results suggest, but do not prove, that the reduced drinking response observed in estrogen-treated rats may be related to a reduction in the number of Ang II receptors in the brain. Expand
Effects of adrenergic agonists and antagonists on muscle O2 uptake and lactate metabolism.
TLDR
To investigate adrenergic receptor-mediated responses in dog gastrocnemius-plantaris muscle, several catecholamine agonists, isoproterenol, epinephrine, norepinephrine, and phenylephrine were given during repetitive, isotonic, tetanic contractions, and two antagonists, propranolol and phenoxybenzamine were given. Expand
Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats.
TLDR
Results suggest that chronic administration of L-5-HTP provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats. Expand
Structure-Activity and Conformational Requirements for Dopaminergic Agonists; Comparison of Central and Peripheral Dopamine Receptors
ABSTRACT The structure-activity requirements for dopamine-like activity in a range of systems, including a simple peripheral model, has been studied. In all systems examined there is an absoluteExpand
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