• Publications
  • Influence
Moving towards an integrated approach to molecular detection and identification of Toxoplasma gondii.
The development of simple, sensitive and rapid methods for the detection and identification of Toxoplasma gondii is important for the diagnosis and epidemiological studies of the zoonotic diseaseExpand
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Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America.
Toxoplasma gondii is a widespread parasite of animals that causes zoonotic infections in humans. Previous studies have revealed a strongly clonal population structure in North America and Europe,Expand
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Genetic diversity, clonality and sexuality in Toxoplasma gondii.
The majority of Toxoplasma gondii strains from a variety of human and animal sources have been grouped into three highly clonal but closely related lineages. The low occurrence of nucleotideExpand
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Genotyping of Toxoplasma gondii by multilocus PCR-RFLP markers: a high resolution and simple method for identification of parasites.
It was generally believed that Toxoplasma gondii had a clonal population structure with three predominant lineages, namely types I, II and III. This was largely based on genotyping of more than 100Expand
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A Secreted Serine-Threonine Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii
Toxoplasma gondii strains differ dramatically in virulence despite being genetically very similar. Genetic mapping revealed two closely adjacent quantitative trait loci on parasite chromosome VIIaExpand
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Population structure and mouse-virulence of Toxoplasma gondii in Brazil.
Recent studies found that isolates of Toxoplasma gondii from Brazil were biologically and genetically different from those in North America and Europe. However, to date only a small number ofExpand
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Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages
  • C. Su, A. Khan, +8 authors L. Sibley
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 19 March 2012
Marked phenotypic variation characterizes isolates of Toxoplasma gondii, a ubiquitous zoonotic parasite that serves as an important experimental model for studying apicomplexan parasites. Progress inExpand
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Toxoplasmosis in humans and animals in Brazil: high prevalence, high burden of disease, and epidemiology.
Infections by the protozoan parasite Toxoplasma gondii are widely prevalent in humans and animals in Brazil. The burden of clinical toxoplasmosis in humans is considered to be very high. The highExpand
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Recent transcontinental sweep of Toxoplasma gondii driven by a single monomorphic chromosome
  • A. Khan, B. Fux, +5 authors L. Sibley
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 11 September 2007
Toxoplasma gondii is a highly prevalent protozoan parasite that infects a wide range of animals and threatens human health by contaminating food and water. A markedly limited number of clonalExpand
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Biologic and genetic comparison of Toxoplasma gondii isolates in free-range chickens from the northern Pará state and the southern state Rio Grande do Sul, Brazil revealed highly diverse and distinct
The prevalence of Toxoplasma gondii in 84 free-range chickens (34 from the northern Pará state, and 50 from Rio Grande do Sul, the southern state) from Brazil, South America was determined.Expand
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